New study explores less drastic option for deadly pregnancy disorder
NCT ID NCT05139498
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tests whether leaving the placenta in place after delivery (conservative management) is a safe and effective alternative to hysterectomy for women with placenta accreta spectrum, a condition where the placenta grows too deeply into the uterine wall. Four participants were enrolled to see if a larger trial is feasible. The goal is to provide better data for shared decision-making and reduce the need for major surgery.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
4 people
The number who actually took part.
- Started
-
May 2022
- Expected to finish
-
Jun 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 99 years
- Sex
-
Female participants only
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 and older * History of cesarean delivery AND placenta previa OR anterior low-lying placenta AND suspected of having PAS on prenatal imaging (ultrasound/MRI) * Patients who would typically be recommended for hysterectomy * Planned delivery between 34w0d and 36w0d gestation. Exclusion Criteria: * Plan to delivery before neonatal viability (\<24 weeks gestation) * Hospitalized for antenatal hemorrhage * Have a low antenatal suspicion for PAS based on imaging * Are pregnant with multiples (twins, triplets) * Have a uterine fetal demise
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Placenta accreta are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Utah
Salt Lake City, Utah, 84132, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can 3D ultrasound spot dangerous placenta conditions better?
- Can a targeted nerve block cut opioid use in High-Risk C-Sections?
- Womb healing after placenta accreta: a closer look
- Quick clot test may help women during High-Risk delivery surgery
- New study aims to predict dangerous placenta complications before delivery
- New surgery map for dangerous placenta condition tested