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Large study aims to uncover who is most at risk from listeria infection

NCT ID NCT01520597

Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at over 2,100 people with listeriosis, a serious foodborne infection that can cause blood infections, brain infections, and pregnancy complications. Researchers collected data to find out which clinical, biological, and genetic factors make someone more likely to get sick or die from the disease. The goal was to better understand who is at highest risk and improve future care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

2,132 people

The number who actually took part.

Started

Nov 2009

Finished

Jul 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Case: patient with culture-proven listeriosis (blood CSF, fetal/placental sample, other…). Controls: patient above the age of 18 years with medical background and clinical features compatible with one of the 3 forms of systemic listeriosis: febrile pregnant women (temp \> 38°C), febrile patient with co-morbidity for septicaemic listeriosis, and any febrile symptom leading to empiric amoxicillin prescription.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Case: * Patient with culture-proven listeriosis (blood, CSF, fetal/placental sample, other…). Control: * Patient above the age of 18 years with medical background and clinical features compatible with one of the 3 forms of systemic listeriosis: febrile pregnant women (temp \> 38°C), febrile patient with co-morbidity for septicaemic listeriosis, and any febrile symptom leading to empiric amoxicillin prescription. * For feasibility reasons, controls are included in Paris (France) emergency wards. Exclusion Criteria: Case: * Patient who would refuse to sign informed consent agreement Control: * Patient who would refuse to sign informed consent agreement, or whose samples would evidence L. monocytogenes

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Conditions

The condition(s) this trial relates to.

bacterial infectious disease with sepsis central nervous system infectious disorder infectious disease listeriosis pregnancy disorder Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Central nervous system infections Infectious Listeriosis Pregnancy complications Sepsis; listeria monocytogenes Septicemia

Contacts and locations

Locations

  • Centre National de Reference et Centre Collaborateur OMS Listeria, Institut Pasteur

    Paris, 75015, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.