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Blood marker may flag dangerous preeclampsia

NCT ID NCT06413576

Diagnosis Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether measuring homocysteine levels in the blood can help predict how severe preeclampsia will become in pregnant women. Researchers measured homocysteine in 70 critically ill preeclampsia patients and analyzed its link to complications. The goal is to see if this simple test could help doctors identify high-risk patients earlier.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple blood test to help doctors identify which preeclampsia patients are at highest risk of complications.
What could go wrong
This is a small, completed observational study, not a treatment trial. The findings need to be confirmed in larger, more diverse groups before any test could be widely used.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

70 people

The number who actually took part.

Started

Jan 2024

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

pregnant females with pre-eclampsia and within 24 hours of delivery

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All patients diagnosed by preeclampsia will be included in light of the following diagnostic criteria (blood pressure more than 140\\90 mm\\Hg on 2 occasions at least 4 hours apart after 20 weeks' gestation in a previously normotensive patient accompanied by Protein/creatinine ratio ≥0.3 . Exclusion Criteria: * Essential hypertension suggested by history or documentation of hypertension in pre pregnant state or hypertension before 20 weeks of gestation. * Cardiovascular or renal failure * Liver failure * Diabetes mellitus * Inflammatory or infective disorders * History or documentation of epilepsy in prepregnant state * Space occupying lesion in brain like tuberculoma or brain tumor * Trauma to brain * Hyperpyrexia * On treatment with antifolate drugs such as methotrexate

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Conditions

The condition(s) this trial relates to.

Critical Illness preeclampsia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Critical illness Pre-eclampsia

Contacts and locations

Locations

  • Ain shams University

    Cairo, Cairo Governorate, 11591, Egypt

  • Ain shams university

    Cairo, Cairo Governorate, Egypt

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