Blood markers may spot diabetes risk after pregnancy
NCT ID NCT02133729
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study followed 255 women with gestational diabetes to see if simple blood tests during pregnancy could predict who will develop type 2 diabetes after giving birth. Researchers measured three markers (CRP, MDA, and adiponectin) and checked glucose tolerance three months after delivery. The goal is to focus follow-up care on women at highest risk.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors identify which women with gestational diabetes are at highest risk for type 2 diabetes, allowing earlier prevention efforts.
- What could go wrong
- This is an observational study, not a treatment trial. The markers tested may not prove accurate enough for routine use, and results may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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255 people
The number who actually took part.
- Start date
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Jun 2011
- Finished
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Apr 2015
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Women aged over 18years old * Women with the criteria of GDM during pregnancy at 21-35 weeks of gestation (one situation): * After a 75g Oral Glucose Tolerance Test (OGTT - WHO criteria) with blood glucose (BG) values at T60≥180mg/dl and/or T120≥153mg/dl * An O. Sullivan test following a 100g oral glucose load with at least two pathological values (T60 ≥ 180mg/dl and/or T120 ≥ 155mg/dl and/or T180 ≥ 140mg/dl) * With a fasting BG value ≥92mg/dl * Women with signed informed consent Exclusion Criteria: * Women aged less than 18years old * Women with pregestational type 2 diabetes * Women without signed informed consent * Women who does not read and/or understand french language * Women not affiliated to the health care system * Women with recent infection (\<1month) and/or on steroids or anti-inflammatory drugs. * Women with chronic diseases * Women with a disable state * Women with normal glucose tolerance * Women already incorporated in another clinical study that could interfere with the present study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU Clermont-Ferrand - Hôpital Gabriel Montpied - Service d'endocrinologie
Clermont-Ferrand, 63003, France
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CHU Grenoble - Clinique d'Endocrinologie Diabétologie Nutrition
Grenoble, 38000, France
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CHU Saint Etienne - Hôpital Nord - Service d'endocrinologie, diabètes, nutrition
Saint-Etienne, 42055, France
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Centre Hospitalier de Givors - Hôpital de Montgelas - Service de médicine 8
Givors, 69700, France
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Groupement Hospitalier des Portes du Sud - Service d'Endocrinologie Diabétologie Nutrition
Vénissieux, 69200, France
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Hospices Civils de Lyon - Groupement Hospitalier Sud - Service d'Endocrinologie, Diabète, Nutrition
Pierre-Bénite, 69495, France
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Hospices Civils de Lyon - Hôpital Femme-Mère-Enfant - Service de gynécologie obstétrique
Bron, 69677, France
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