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New mom depression? light therapy and sleep fixes show promise without drugs

NCT ID NCT04364646

First seen Dec 29, 2025 · Last updated May 21, 2026 · Updated 17 times

Summary

This study tested a non-drug treatment called Personalized Integrated Chronotherapy (PIC) for pregnant women with depression. PIC combines bright light therapy, sleep schedule changes, and sleep stabilization. 120 pregnant women with major depression were randomly assigned to receive either usual care (medication or talk therapy) or PIC plus usual care. The goal was to see if adding PIC improves mood and sleep, and to check its safety.

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Contacts and locations

Locations

  • Feinstein Institute For Medical Research

    Glen Oaks, New York, 11004, United States

  • Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27599, United States

Conditions

Explore the condition pages connected to this study.