New mom depression? light and sleep therapy shows promise without drugs

NCT ID NCT04364646

First seen Dec 29, 2025 · Last updated May 09, 2026 · Updated 15 times

Summary

This study tested a non-drug treatment called Personalized Integrated Chronotherapy (PIC) for depression during pregnancy and after childbirth. 120 pregnant women with major depression received either usual care (medication or therapy) or PIC plus usual care. PIC combines bright light therapy, adjusting sleep timing, and stabilizing sleep patterns. The goal was to see if PIC improves mood and targets sleep-wake rhythms. Results could offer a safe, non-medication option for perinatal depression.

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Contacts and locations

Locations

  • Feinstein Institute For Medical Research

    Glen Oaks, New York, 11004, United States

  • Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27599, United States

Conditions

Explore the condition pages connected to this study.