Rhode Island Hospital
Clinical trials sponsored by Rhode Island Hospital, explained in plain language.
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Could a 2-Day infusion save transplanted kidneys?
Disease control Recruiting nowThis study tests if a drug called treprostinil can help protect a new kidney from injury during transplant surgery. About 20 adults receiving a deceased donor kidney will get the drug through an IV for two days, starting just before surgery. The goal is to see if it improves kidn…
Phase: PHASE1, PHASE2 • Sponsor: Rhode Island Hospital • Aim: Disease control
Last updated May 26, 2026 06:20 UTC
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Could a higher dose keep more people in opioid treatment?
Disease control Recruiting nowThis study compares a higher daily dose of buprenorphine (24 mg) to the standard dose (16 mg) in 250 adults with opioid use disorder who have used fentanyl. The goal is to see if the higher dose helps people stay in treatment longer and reduces cravings and overdose risk. Partici…
Phase: PHASE2, PHASE3 • Sponsor: Rhode Island Hospital • Aim: Disease control
Last updated May 18, 2026 12:01 UTC
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New video tool aims to stop PTSD and drug use in injured teens
Prevention Recruiting nowThis study is testing two short videos designed to help teens and their parents cope after a traumatic injury. The goal is to prevent posttraumatic stress disorder (PTSD) and substance use. About 92 teens aged 12-17 and their parents will watch the videos and complete surveys ove…
Phase: NA • Sponsor: Rhode Island Hospital • Aim: Prevention
Last updated May 26, 2026 06:20 UTC
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Can vitamins shield transplant patients from skin cancer?
Prevention Recruiting nowThis early-stage trial tests whether taking vitamin A and nicotinamide (a form of vitamin B3) can help prevent skin cancer in kidney transplant recipients who have already had skin cancer. The study will enroll 30 adults and measure changes in blood vitamin levels to see if the s…
Phase: EARLY_PHASE1 • Sponsor: Rhode Island Hospital • Aim: Prevention
Last updated May 26, 2026 06:19 UTC
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New combo may ease hip surgery pain and cut opioid use
Symptom relief Recruiting nowThis study looks at whether adding dexmedetomidine to a standard numbing medicine (ropivacaine) in a nerve block can improve pain relief after hip replacement surgery. About 120 adults having hip surgery will be randomly assigned to receive either the standard nerve block or the …
Phase: PHASE4 • Sponsor: Rhode Island Hospital • Aim: Symptom relief
Last updated May 26, 2026 06:17 UTC
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Could a simple nerve zap ease restless legs in pregnancy?
Symptom relief Recruiting nowThis study is testing whether a small, non-invasive device that stimulates a nerve in the leg can safely and effectively relieve Restless Legs Syndrome (RLS) in pregnant women. Fifteen participants between 21 and 26 weeks pregnant will use the TOMAC™ device for 30-minute sessions…
Phase: NA • Sponsor: Rhode Island Hospital • Aim: Symptom relief
Last updated May 18, 2026 12:03 UTC
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City Kids' asthma linked to sleep duration
Knowledge-focused Recruiting nowThis study looks at how sleep length impacts the immune system and lung function in urban children with asthma. Researchers will test 204 kids aged 7-11 by changing their sleep and measuring immune markers. The goal is to understand why city kids with asthma often have worse symp…
Phase: NA • Sponsor: Rhode Island Hospital • Aim: Knowledge-focused
Last updated May 22, 2026 14:02 UTC