Rhode Island Hospital

This study tested whether the hormone DHEA can improve heart function in people with pulmonary arterial hypertension (PAH), a condition where high blood pressure strains the heart. Twenty-six adults took DHEA or a placebo in two 18-week periods, with a washout in between. The mai…

This study tested two different doses of praziquantel (40 vs 80 mg/kg) in 354 children aged 1-4 years with schistosomiasis, a parasitic infection. The goal was to find a safe and effective dose that could cure the infection and improve growth and nutrition. The trial also looked …

This study tested a program called Guardians 4 Health, which teaches youth and adults in 4-H Shooting Sports Clubs how to step in and prevent firearm injuries. Researchers worked with 801 participants to see if the program changed their intentions to act safely. The goal was to b…

This study tested a program called iDOVE2 for teens at risk of peer violence and depression. It combined a short session in the emergency department with automated text messages to help prevent these issues. The study involved 620 teens and measured changes in violent behavior an…

This study tested whether giving lidocaine through an IV works as well as a numbing shot near the knee (nerve block) for pain after knee replacement. 120 adults having knee surgery were randomly assigned to one of the two methods. The main goal was to see how much opioid pain med…

This study tested a non-drug treatment called Personalized Integrated Chronotherapy (PIC) for pregnant women with depression. PIC combines bright light therapy, sleep schedule changes, and sleep stabilization. 120 pregnant women with major depression were randomly assigned to rec…

This study tested whether a numbing injection near the chest wall (serratus anterior plane block) can improve pain, breathing, and coughing in emergency room patients with broken ribs. Forty adults with rib fractures received either the injection or standard care. Researchers mea…