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New nerve block eases rib fracture pain, cuts opioid use

NCT ID NCT06299137

Symptom relief Sponsor: Rhode Island Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether an ultrasound-guided nerve block (Serratus Anterior Plane Block) can improve pain, breathing, and coughing in emergency room patients with rib fractures. Forty adults with confirmed rib fractures received either the nerve block or usual care. Researchers measured pain and breathing scores over five hours and tracked opioid use over 24 hours to see if the block reduced the need for painkillers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Participants

40 people

The number who actually took part.

Started

Jul 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Radiology confirmed anterior or lateral rib fractures either on X-ray or chest computed tomography CT * pain score of 5/10. * Patients must be able to verbalize how much pain they are having on an 11-point Numeric Rating Pain Scale * perform an incentive spirometry and be able to cough on command Exclusion Criteria: * isolated rib fractures that do not include ribs T3-T9 * penetrating trauma, pregnancy * requiring immediate surgical or procedural intervention * known allergy to amide-type local anesthetics * have a painful distracting injury

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Conditions

The condition(s) this trial relates to.

Acute Pain bone fracture opioid abuse Rib Fractures

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Opioid use Pain, acute Regional anesthesia Rib fractures

Contacts and locations

Locations

  • Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.