Two ways to numb the arm: which nerve block wins for hand surgery?
NCT ID NCT07823738
First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time
Summary
Hand, wrist, and forearm surgeries often cause significant pain, and an axillary nerve block is a standard way to numb the arm. In the classic approach, doctors target the nerves around the axillary artery under ultrasound. A newer interfascial approach deposits anesthetic between the arm muscles instead, aiming for more even spread with fewer needle movements. This randomized study compares the two methods in 110 adults to see which one reliably blocks pain well enough to complete surgery without extra numbing or general anesthesia.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Two ultrasound-guided axillary brachial plexus nerve block techniques: the classic perivascular approach and a modified interfascial approach
- What this could lead to
- If the interfascial approach works better, it could give anesthesiologists a more reliable way to numb the arm for hand, wrist, and forearm surgery, with fewer needle passes and less need for extra painkillers or general anesthesia.
- What could go wrong
- This is a single-center study of 110 people, so its results may not hold in other hospitals or with different surgeons. Nerve blocks can fail partially, cause temporary numbness or weakness, or rarely lead to nerve injury or local anesthetic complications.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 110 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Oct 2026
An estimate. Start dates often move.
- Expected to finish
-
Sep 2027
An estimate. End dates often move.
- Lead sponsor
-
A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 65 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged 18-90 years * American society of anesthesiologists physical status I-II-III * Scheduled for elective hand, wrist, or forearm surgery * Written informed consent obtained Exclusion Criteria: * History of local anesthetic allergy * Coagulation disorder * BMI \> 40 kg/m² * Infection at the block site * Chronic pain syndrome * Pregnancy * Inability to communicate * Need for emergency surgery
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Nerve block are added.
Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Bursa Yuksek Ihtisas Training and Research Hospital
Bursa, 16110, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- AI could forecast spinal block duration, study tests
- Can a pinch of magnesium make nerve blocks last longer?
- Can a steroid extend pain relief after shoulder surgery?
- What happens when spinal anesthesia fails during C-Section? a study listens to mothers
- A 5-Minute video before surgery could ease pain and build trust
- Could opioid tolerance dull the power of local anesthetics?