PREGNANCY RELATED

This study looks at whether delivering medically tailored groceries to pregnant women on Medicaid can reduce food insecurity and improve pregnancy outcomes, like preventing preterm birth and low birthweight. About 360 pregnant women in Cuyahoga County, Ohio, will receive free gro…

This study looks at whether giving pregnant women with sickle cell disease regular blood transfusions can reduce serious complications like pain crises, strokes, and pregnancy problems. About 50 women will be randomly assigned to receive either repeated transfusions or standard c…

This study compares two different programs designed to reduce heart disease risk factors in Black women after pregnancy. Researchers will track changes in blood pressure and body weight at 6 weeks and 12 months after delivery. The goal is to find the best way to support heart hea…

This study looks at 900 women who want permanent birth control during a C-section. It compares two ways to remove the fallopian tubes: using a special energy tool versus traditional stitches. The goal is to see which method is safer and costs less.

This study tests whether giving iron through a vein (IV) early in the second trimester works better than iron pills for treating anemia in pregnancy. About 80 pregnant women with mild iron deficiency will be randomly assigned to one of two treatments. The goal is to see which app…

This study is testing a special camera that uses light to examine the cervix during pregnancy. The goal is to see if it can detect changes that might lead to preterm birth. Researchers will study 683 pregnant women, both at low and high risk of early delivery, to find patterns th…

This study is working to find a better way to detect eating disorders in pregnant women. Right now, it's hard to tell the difference between normal pregnancy food worries and a real eating disorder. Researchers will ask 50 pregnant women (some with and some without an eating diso…

This study aims to develop a blood test that can determine the father of a fetus using a sample of the mother's blood. It is designed for victims of sexual assault who become pregnant and need to know paternity. The test analyzes tiny pieces of the baby's DNA found in the mother'…

This study is testing a program called TENDAI4PrEP to help pregnant women in Zimbabwe take PrEP, a daily pill that prevents HIV. The program combines problem-solving support to address barriers like depression and anxiety. About 132 pregnant women at risk for HIV will participate…

This study tests whether using a pelvic wand for perineal massage during late pregnancy and labor can help women feel more in control during childbirth. Researchers will compare the experiences of 140 pregnant women who either receive standard care or add this massage technique. …

This study tests whether a buprenorphine patch can reduce withdrawal symptoms in pregnant women starting treatment for opioid use disorder. About 40 participants will use the patch during the required withdrawal period before switching to standard under-the-tongue buprenorphine. …

This study tests whether taking progesterone (a hormone) after intrauterine insemination (IUI) can increase the chance of a live birth for couples with unexplained infertility. About 1008 women will be randomly assigned to receive either progesterone or no extra treatment. The go…

This study looks at whether sexual counseling during pregnancy can help improve sexual function, reduce depression and anxiety, and strengthen relationships. About 70 pregnant women will receive two group counseling sessions or standard care. The goal is to address common myths a…

This study tests whether a smartphone app called BumptUp can help pregnant and postpartum women living in rural areas become more physically active. About 176 women will either use the app or receive an educational brochure. Researchers will track activity levels, weight, diet, b…

This study compares two types of exercises—diaphragmatic breathing and pelvic stabilization—delivered via real-time telehealth to help postpartum women with pregnancy-related pelvic girdle pain. Sixty women who are at least 3 months postpartum and have pelvic pain will participat…

This study monitors the health of women who took the heart medication mavacamten during pregnancy or while breastfeeding, along with their babies. Researchers will track pregnancy complications, birth outcomes, and infant development through the first year of life. The goal is to…

This study tests whether wrist-worn devices can safely monitor pregnant women with congenital heart disease at home. Researchers will track heart rhythms and other data from 50 participants to see if early warning signs of complications can be detected. The goal is to improve car…

This study looks at how pregnant and non-pregnant patients recover after being in the intensive care unit (ICU) for COVID-19 and lung failure. Researchers will track problems with movement, thinking, and mental health for up to 3 years after the ICU stay. The goal is to better un…

This study talks to 60 women who gave birth in French-speaking Belgium within the last year to understand why they chose their birth place (home, birth center, or hospital) and what their experience was like. Researchers also interview birth companions like doulas and midwives to…

This study uses MRI scans to measure pancreas size in pregnant women and their unborn babies. Researchers want to see how the pancreas changes during pregnancy and how those changes are linked to diabetes. The goal is to better understand diabetes risk for both mother and child. …

This study aims to understand how cells in the human placenta change during pregnancy by analyzing gene activity. Researchers will collect small placenta samples from 100 women in early pregnancy and at childbirth. The goal is to create a detailed map of cell communication and fi…

This study looks at whether a program originally used in clinics can work in community settings to help pregnant women with healthy eating and exercise. Researchers will test the program with 60 expecting mothers who have a BMI over 30. The goal is to see if the program is easy t…

This study watches for any health problems in pregnant or breastfeeding women who have taken the drug odevixibat, and in their babies. It does not give any new treatments or tests—just collects information from regular doctor visits. About 20 people will take part to help underst…

This study follows 100 pregnant women with opioid use disorder who are already receiving standard treatment. Researchers will track whether mothers relapse and whether their babies develop withdrawal symptoms (NOWS). The goal is to better understand and eventually prevent these o…

This study tests whether adjusting room light (bright or dim/red) can influence uterine contractions and melatonin release in pregnant women. Researchers aim to find light settings that help labor progress or slow it down. About 100 healthy pregnant women aged 18-42 will use home…

This study looks at whether pregnant women with complications (like high blood pressure or slow baby growth) can use a simple, self-administered heart monitor at home instead of staying in the hospital. About 60 participants will use the device daily, record their blood pressure …

This study aims to develop a smarter computer program that can separate a baby's heartbeat from the mother's during pregnancy. Researchers will collect heart recordings from 350 pregnant women to train and test the AI. The goal is to make fetal monitoring more accurate and reliab…

This study follows 60 women with NMOSD who received UPLIZNA during pregnancy or within 6 months before getting pregnant. Researchers will collect information on pregnancy outcomes, such as birth defects, preterm birth, and low birth weight. The goal is to better understand the sa…

This study is a registry that will enroll up to 1,000 pregnant women or those planning pregnancy who have autoimmune diseases like lupus or rheumatoid arthritis. Researchers at Duke University will collect information to identify risk factors for poor pregnancy outcomes. The goal…

This study aims to adapt a program called Staying Healthy After Childbirth (STAC) to better serve Black women and birthing persons. Researchers will work with community groups and staff to identify barriers and helpful factors, and then test small changes. The goal is to improve …

This study is observing 242 pregnant women to learn how the heart and blood vessels change during pregnancy and after delivery. Researchers will use non-invasive tests like heart rate monitoring and ultrasound to track these changes. The goal is to better understand normal heart …

This study will follow about 9,500 women in Kalifabougou, Mali, to track pregnancy outcomes and malaria infections. Researchers will collect data through home visits and at a local health center. The goal is to better understand how malaria affects pregnancy and to improve care f…

This study looks at how mothers with HIV in the United States decide to feed their babies, whether by breastfeeding or formula. Researchers will interview and survey about 1,150 mothers and their families to understand the medical, social, and personal factors behind these choice…

This study looks at over 5,600 pregnant women with eczema to see if using ruxolitinib cream affects the baby's health compared to using standard steroid creams. Researchers will track birth defects, birth weight, and pregnancy outcomes using insurance claims data. The goal is to …

This study tests whether small wearable sensors can safely track movement and walking in pregnant women during early labor while they have a low-dose epidural. Researchers will measure how gait changes with pain and medication. The goal is to improve monitoring, prevent falls, an…

This study follows 825 pregnant women who need blood thinners for blood clots to see how doctors manage their medication around childbirth. The goal is to learn which strategies lead to fewer bleeding problems. No new treatments are tested; instead, researchers observe real-world…

This study follows about 958 pregnant women with mild to moderate eczema to see if using ruxolitinib cream affects pregnancy or baby health. Researchers compare those who used the cream with those who did not, focusing on birth defects and other outcomes. The goal is to gather sa…

This study tests whether a tool called MyPath helps women with substance use disorder make and stick with a birth control plan after giving birth. About 400 women will use the tool or receive standard care. The goal is to see if MyPath improves consistent use of effective contrac…

This study follows pregnant women who take tildrakizumab for approved conditions and compares them to pregnant women with the same condition who do not take the drug. Researchers track pregnancy outcomes and infant health up to one year after birth. The goal is to understand if t…

This study looks at whether simulation training for doctors, nurses, and midwives can reduce the number of cervical exams women receive during labor and make exam results more consistent. Over 1,100 healthcare providers and patients will take part. The goal is to improve care by …