PREGNANCY RELATED

This study compares two surgical techniques for permanent sterilization performed during cesarean delivery. Researchers are looking at 900 women who requested sterilization during their C-section to see if using a bipolar energy device leads to better recovery outcomes than tradi…

This study is testing a digital tool called MyPath that helps women with substance use disorders make informed decisions about contraception after giving birth. The tool guides women through thinking about their pregnancy goals, learning about fertility, and choosing contraceptiv…

This study is testing if a buprenorphine skin patch can help pregnant women with opioid addiction start treatment with less severe withdrawal symptoms. Normally, patients must go through withdrawal before beginning medication, but the patch may ease this difficult period. Researc…

This study is testing a special mobile app designed for Black pregnant women. The app provides culturally relevant tools to build self-advocacy skills, improve communication with doctors, and create a support network. Researchers want to see if using the app can help reduce depre…

This study is testing whether getting iron through an IV is better than taking iron pills for pregnant women with low iron. Researchers want to see which method improves blood counts more effectively, causes fewer side effects, and leads to a better quality of life. About 80 wome…

This study is testing whether adding progesterone hormone support after IUI fertility treatment helps more couples have babies. It involves over 1,000 couples with unexplained infertility who are undergoing standard fertility treatment. Half will receive the progesterone treatmen…

This study is testing if simple changes to room lighting can help labor progress more successfully. Researchers believe dim or red light might help the body's natural processes, potentially leading to more vaginal births and fewer C-sections. They are enrolling 100 healthy pregna…

This study aims to reduce heart disease risk for Black women during and after pregnancy. Researchers will compare two support programs for 432 Black mothers with high blood pressure or obesity. One program provides basic health coaching, while the other adds community doula care,…

This study aims to develop and validate a new blood test for pregnant women that can determine the paternity of their baby. The test analyzes tiny bits of the baby's DNA found in the mother's blood, offering a non-invasive alternative to riskier procedures. The research is specif…

This study is testing a new type of camera called a Mueller polarimetric colposcope to see if it can predict when a pregnant person will give birth. Researchers want to see if images of the cervix can create a 'score' that accurately forecasts delivery date and identifies risk of…

This study is testing whether a healthy lifestyle program for women with overweight or obesity, started before they get pregnant, can help prevent their future children from developing obesity. Researchers will compare women who receive diet, exercise, and mentorship support to t…

This study is testing whether a healthy lifestyle program designed for pregnant women with obesity can be successfully delivered in community settings instead of just clinics. Researchers will work with community members to adapt the program and then test it with 60 expecting mot…

This study aims to find out if giving regular blood transfusions during pregnancy can prevent health crises and pregnancy complications in women with sickle cell disease. Researchers will compare two groups: one receiving scheduled transfusions and another receiving standard care…

This study aims to adapt and improve a health program called 'Staying Healthy After Childbirth' (STAC) specifically for Black women and birthing persons. Researchers will work closely with community members and a small group of participants to gather feedback on how to best imple…

This study is testing if delivering healthy groceries directly to the homes of pregnant women who struggle to afford food can improve their health and their babies' health. It will enroll 360 pregnant women in Ohio who are eligible for Medicaid. Researchers will compare different…

This study is comparing two methods of epidural pain relief for women in labor. It aims to see if a newer technique called Dural Puncture Epidural (DPE) provides faster and better pain relief than the standard epidural. Researchers will measure pain levels, side effects, and how …

This study is testing whether a mobile app called BumptUp can help pregnant and postpartum women in rural areas get more physical activity. Researchers will compare the app to an educational brochure to see which is better at increasing activity levels. They will also check if us…

This study is testing whether using a special pelvic wand for perineal massage in late pregnancy and during labor helps people feel more in control of their birth process. Researchers will compare two groups of about 140 pregnant participants: one using the wand and one receiving…

This study is testing whether a prenatal yoga app can improve the well-being of first-time Black and African American pregnant women. Researchers want to see if using the app for 12 weeks is practical and helps with stress, mood, and physical health. The study also aims to learn …

This study aims to understand if using ruxolitinib cream for eczema during pregnancy affects the baby's health. Researchers will compare pregnancy outcomes between women who used the cream and those who did not. The study is observational, meaning it tracks what happens naturally…

This registry aims to understand how autoimmune diseases like lupus and rheumatoid arthritis affect pregnancy. Researchers will follow 1,000 pregnant women with these conditions to identify factors linked to poor outcomes. The study collects information from regular doctor visits…

This study aims to understand the safety of the drug odevixibat for pregnant and breastfeeding individuals and their babies. It will collect information from medical records of about 20 people who took the drug during pregnancy or while nursing. The study is purely observational,…

This study aims to understand the safety of a newer eczema cream (ruxolitinib) during pregnancy by comparing it to standard steroid creams. Researchers will analyze health insurance claims data from over 5,600 pregnant women in the US who have atopic dermatitis (eczema). The stud…

This study aims to test if small wearable sensors can accurately measure how women walk and move during the first stage of labor. Researchers want to see if these sensors work for women both with and without low-dose epidural pain relief. The goal is to gather basic movement data…

This study aims to understand how mothers living with HIV in the U.S. make decisions about feeding their babies, including breastfeeding. Researchers will interview mothers, healthcare providers, and family members, and follow a large group of mothers and infants to learn about t…

This study aims to understand how blood thinners are managed around childbirth in pregnant women with a history of blood clots. Researchers will follow 825 women to track bleeding risks, new clot formation, and patient experiences during delivery and recovery. The goal is to gath…

This study aims to understand why some pregnant women with opioid use disorder relapse and why some babies develop withdrawal symptoms, while others do not. Researchers will follow 100 pregnant women already receiving standard medication treatment and their infants for one year, …

This study aims to gather detailed information about pregnancy and malaria in a community in Mali. Researchers will follow up to 9,500 women of childbearing age and their babies for several years to track health outcomes. The data collected will help plan future clinical trials t…

This study aims to understand why women in Belgium choose specific places to give birth and to learn about their overall childbirth experiences. Researchers are interviewing women who have given birth within the last year, as well as birth professionals like doulas and midwives. …

This study aims to understand how the heart and blood vessels naturally change during a healthy pregnancy and after birth. Researchers will measure heart rate patterns and blood pressure in 242 pregnant participants to create a detailed picture of normal adaptation. The goal is t…

This study aims to understand how the pancreas changes size during pregnancy and how this relates to diabetes risk. Researchers will use MRI scans to track pancreas size in about 87 pregnant women and their developing babies from early pregnancy until one year after birth. The go…

This study is testing if a smart wristband can help monitor the heart health of pregnant women who were born with a heart condition. The goal is to see if the device can spot early warning signs of heart problems while women are at home. Researchers will enroll 50 participants to…

This study is testing whether a new training program for doctors, nurses, and midwives leads to better care for women in labor. All staff in a specific hospital's labor and delivery unit will practice cervical exams on a simulator until they reach a set skill level. Researchers w…

This study aims to understand the long-term recovery challenges faced by patients who survived severe COVID-19 requiring intensive care. Researchers are comparing about 13 pregnant patients with about 27 non-pregnant patients to see if pregnancy affects recovery in areas like phy…

This study aims to understand the safety of the heart medication mavacamten during pregnancy and breastfeeding. Researchers will follow about 20 people who took the drug while pregnant or nursing, tracking the health of both the parent and baby for up to a year after birth. This …

This study aims to understand the safety of the NMOSD medication UPLIZNA during pregnancy. It will follow about 60 women who received the drug while pregnant or just before conception. Researchers will collect information over 10 years to monitor birth outcomes and infant health,…

This study aims to understand the safety of the medication tildrakizumab during pregnancy. Researchers will follow 200 pregnant women who are taking the drug for approved skin conditions and compare their pregnancy and infant outcomes to similar women not taking the drug. The goa…

This study aims to develop better tools to identify eating disorders in pregnant women. Researchers will compare answers from pregnant women with diagnosed eating disorders to those without, using two standard questionnaires. The goal is to find questions that specifically detect…

This study is testing whether pregnant women with complications can successfully use a special home device to monitor their baby's heart rate. The goal is to see if this remote monitoring is a practical option that could reduce hospital visits. Researchers will enroll 60 women be…