Could a simple vitamin help pregnant women with high blood pressure?
NCT ID NCT05434195
First seen May 08, 2026 · Last updated Jun 23, 2026 · Updated 7 times
Summary
This study looks at whether a special form of folic acid (5-MTHF) can improve blood vessel health in pregnant women with high blood pressure or pre-eclampsia. Researchers will measure key molecules in the blood, placenta, and umbilical cord to see if the supplement helps. The trial involves 128 women and aims to understand how the supplement affects the body, not to cure the condition.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cardiovascular Clinical Research Facility
RECRUITINGOxford, Oxfordshire, OX3 7RD, United Kingdom
Contact Email: •••••@•••••
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Oxford University Hospitals NHS Foundation Trust
RECRUITINGOxford, Oxfordhsire, OX3 9DU, United Kingdom
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
5-methyltetrahydrofolate (a form of folic acid)
What this could lead to
If it works, this could point toward a simple nutritional supplement to help manage high blood pressure in pregnancy and protect the heart health of mothers and their babies.
What could go wrong
This is a small, early-stage study focused on measuring biological markers, not on preventing or curing the condition. The supplement may not lead to clear health improvements, and results may not apply to all pregnant women.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.