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Olive power: could a natural supplement ease pregnancy hypertension?

NCT ID NCT07074548

Disease control Sponsor: Dr Cipto Mangunkusumo General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether hydroxytyrosol, a natural antioxidant found in olives, can reduce inflammation and oxidative stress in pregnant women with high blood pressure. 42 women took either a daily 10 mg hydroxytyrosol capsule or a placebo for 4 weeks. Researchers measured changes in blood markers of inflammation and blood pressure to see if the supplement offers any benefit.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
hydroxytyrosol (a natural antioxidant from olives)
What this could lead to
If it works, this could point toward a simple, natural supplement to help manage blood pressure and inflammation in pregnant women with hypertension.
What could go wrong
This is a small, early-stage trial with only 42 participants. The results may not apply to all pregnant women, and the supplement may not significantly improve outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

42 people

The number who actually took part.

Started

Jul 2025

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

24 to 45 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Singleton pregnancy with a live intrauterine fetus 2. Gestational age over 24 weeks. Gestational age is confirmed based on: * Last Menstrual Period (LMP) * First trimester ultrasound biometry 3. Belongs to the Hypertensive Disorders of Pregnancy group, with the following criteria: * Gestational hypertension and preeclampsia according to ACOG 2018 criteria * Chronic hypertension according to ACOG 2019 criteria * Superimposed preeclampsia according to ACOG 2018 criteria Exclusion Criteria: 1. Pregnancy with infection, including chronic infections such as tuberculosis (TB), HIV, or hepatitis B 2. Pregnancy with other complications (e.g., diabetes mellitus, heart disease, kidney disease, liver disease, malignancy, autoimmune disorders) 3. Refusal to participate in the study

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Conditions

The condition(s) this trial relates to.

hypertension, pregnancy-induced hypertensive disorder preeclampsia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hypertension in pregnancy

Contacts and locations

Locations

  • Dr. Cipto Mangunkusumo National Central Public Hospital

    Jakarta Pusat, Jakarta Special Capital Region, 10430, Indonesia

More trials for these conditions

Other studies related to the condition(s) this trial covers.