Could a simple hospital test after birth stop diabetes before it starts?
NCT ID NCT06457139
First seen Jun 26, 2026 · Last updated Aug 14, 2026 · Updated 2 times
Summary
This study tests whether screening women for type 2 diabetes while they are still in the hospital after giving birth can help catch the disease early and prevent it. About 116 women who had gestational diabetes will be randomly assigned to either early testing or usual care. The goal is to see if immediate screening leads to better detection and prevention of type 2 diabetes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- glucose tolerance test
- What this could lead to
- If successful, this could show that screening for diabetes right after childbirth helps catch and prevent type 2 diabetes earlier in women who had gestational diabetes.
- What could go wrong
- This is a small, early-stage study focused on testing the screening process, not a treatment. It may not prove that early screening actually prevents diabetes long-term.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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116 people
The number who actually took part.
- Started
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Jun 2025
- Finished
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Aug 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * pregnancy complicated by GDM as diagnosed with traditional two step testing in the third trimester according to Carpenter-Coustan Criteria * receiving prenatal care at UMASS Memorial and plans to deliver at UMASS Memorial * able and willing to provide informed consent * ability to complete immediate in hospital postpartum glucose testing * have evidence of impaired glucose metabolism defined as fasting glucose value of ≥126 mg/dL or 2-hour glucose value of ≥200 mg/dL Exclusion Criteria: * known diagnosis of pre-existing pre-gestational diabetes in pregnancy * inability to complete oral glucose tolerance test (e.g. gastric bypass surgery history, gastric dumping syndrome history, vomiting of oral glucose tolerance test) in pregnancy or immediately postpartum * systemic steroid use
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Massachusetts Memorial Medical Center
Worcester, Massachusetts, 01605, United States
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