POSTOPERATIVE PAIN

This study tested whether using a mesh patch to reinforce the surgical site during stoma reversal reduces the risk of incisional hernia, infection, and pain compared to standard closure. Sixty-two patients with temporary stomas took part. The goal is to improve recovery and reduc…

This study looked at 154 men having robot-assisted prostate removal. Researchers compared giving a combination of acetaminophen and ibuprofen either before surgery started or right after. The goal was to see if earlier dosing could lower the amount of strong opioid painkillers ne…

This study tested whether aromatherapy foot massage could reduce pain, improve sleep, and speed up recovery in 103 adults who had their gallbladder removed. Participants received the foot massage after surgery, and their pain, sleep quality, and recovery were measured. The goal w…

This study looked at whether keeping the operating room quiet during general anesthesia can lower the chance of moderate to severe pain after major abdominal surgery. Researchers studied 304 adults aged 18 to 70 who were having elective surgery. They measured pain levels and pain…

This study looked at two methods of numbing the suprascapular nerve to control pain after shoulder surgery. Sixty adults having shoulder arthroscopy received either an anterior or posterior nerve block. Researchers measured pain levels and safety, including effects on breathing, …

This study looked at whether adding magnesium sulfate to a local anesthetic nerve block could better control pain after breast removal surgery. Seventy women having a modified radical mastectomy received either the standard nerve block or one with added magnesium. The goal was to…

This study tested whether a numbing medicine called ropivacaine, placed inside the chest during surgery, can reduce severe pain after lung cancer surgery. 90 adults having lung surgery for cancer took part. The main goal was to see how many patients had major pain when moving aft…

This study looked at whether a special nerve block (erector spinae plane block) can reduce pain after lower back surgery. 102 adults were randomly assigned to get the block or standard pain medicine. The goal was to see if the block leads to less pain, less need for strong painki…

This study looked at 142 adults who needed a root canal on a single-root tooth. They were given either octenidine or chlorhexidine as a final rinse during the procedure. The goal was to see which rinse led to less pain in the first 48 hours after treatment. Participants rated the…

This study tested if elastic therapeutic taping can reduce pain after coronary artery bypass surgery. 195 patients were randomly assigned to receive real tape, fake tape, or another supportive treatment. Neither patients nor researchers knew who got which treatment. The goal was …

This study compared two types of nerve blocks (ESPB and Rhomboid) to see which one works better for pain and reduces the need for strong painkillers after lung surgery. 76 adults having lung surgery took part. The goal was to find a better way to manage pain after the operation.

This study looked at 29 healthy adults who needed both lower wisdom teeth removed. One side got a platelet-rich fibrin (PRF) gel, the other a collagen sponge, to see which helped the socket heal better. Researchers measured pain, swelling, and bone healing on x-rays. The goal is …

This study tested whether adding a rectus sheath block (a type of nerve block) to general anesthesia can reduce pain and the need for strong painkillers after abdominal surgery. 46 adults having a midline incision laparotomy took part. The block uses numbing medicine injected nea…

This study looked at whether giving a low dose of magnesium sulfate during lower back surgery can help reduce pain afterward. Sixty adults having lumbar spine surgery received either magnesium or a placebo. The goal was to see if magnesium could lower pain scores and the need for…

This study tested a pain-relief method called TENS-WAA, which uses mild electrical pulses on the skin based on acupuncture points, to see if it can ease pain after lung cancer surgery. 156 adults who had keyhole lung surgery received either the real treatment or a fake device. Th…

This study tested a new type of nerve block, called RISS, to see if it helps control pain after video-assisted chest surgery. 90 adults were randomly assigned to receive either the RISS block plus general anesthesia or general anesthesia alone. The goal was to see if the block re…

This study tested whether a short virtual reality session could help patients feel better after a liver transplant. 84 patients were split into two groups: one group used VR for 20 minutes, the other received standard care. Researchers measured pain, fatigue, and vital signs befo…

This study tested two different methods (paracoracoid vs. costoclavicular) for placing tiny tubes near nerves to deliver pain medicine after hand surgery. 140 adults having hand surgery took part. The goal was to see which method provides better numbness and pain relief, helping …

This study looked at whether using a surgical drain after knee replacement affects pain levels. 60 patients over 60 years old were included. The goal was to see if drains actually help reduce pain in the early days after surgery, since their benefit is still debated.

This study tested whether a superficial cervical block—a simple injection of numbing medicine in the neck—can reduce the need for strong painkillers (opioids) after anterior cervical discectomy surgery. Sixty adults undergoing this surgery were randomly assigned to receive either…

This study looked at 108 adults who needed a root canal on a back tooth. After standard cleaning, half got a final rinse with a traditional needle and half with an ultrasonic device. The goal was to see which method led to less pain after the procedure. Results will help dentists…

This study looked at whether listening to relaxing classical music could help new mothers feel less pain and anxiety after a cesarean delivery. 110 women who had just had their first baby by C-section took part. Starting 24 hours after birth, one group listened to music for 15 mi…

This study tested three simple, drug-free ways to manage pain after knee replacement surgery: using a virtual reality headset, squeezing a soft toy, or listening to poetry. 140 adults were split into four groups to compare these methods with standard care. The main goal was to se…

This study tested a special nerve block (SPSIP block) against standard numbing medicine for people getting a port catheter, a device used for long-term medication. 66 adults took part to see which method caused less pain during the procedure. The goal was to find a better way to …

This study tested whether adding ketamine to general anesthesia helps reduce the need for morphine and lowers pain after breast cancer surgery. About 230 adults having mastectomy or lumpectomy took part. The goal was to see if ketamine could make recovery less painful and reduce …

This study looked at two types of nerve blocks—fascia iliaca block and femoral nerve block—to see which one works better for pain control in people having hip fracture surgery. 80 adults were randomly assigned to receive one of the two blocks before spinal anesthesia. The main go…

This study tested whether an ultrasound-guided nerve block (external oblique intercostal plane block) could reduce pain after kidney surgery. 25 adults were randomly assigned to receive either the nerve block or standard morphine. The goal was to see how long pain relief lasted a…

This study looked at whether applying ice packs to surgical cuts every 4 hours for 3 days helps adults recover better after chest, belly, or groin surgery. 196 patients took part, with some getting ice plus standard care and others standard care alone. The main goal was to see if…

This study tested a new type of nerve block, called M-TAPA, to see how well it controls pain after a laparoscopic hysterectomy. Fifty women having the surgery received the block, and their pain was measured over 24 hours. The goal was to find a better way to manage pain after thi…

This study looked at 93 adults having bladder tumor surgery under spinal anesthesia. They were given either magnesium sulfate, dexmedetomidine, or a placebo during the operation. Magnesium sulfate led to less pain after surgery, delayed the need for extra painkillers, and reduced…

This study tested a long-acting painkiller called dinalbuphine sebacate in 634 adults having surgery. The goal was to see if better pain control could reduce complications like pneumonia and infections, and help patients heal faster. Researchers measured pain levels and painkille…

This study looked at whether adding a ketamine infusion to standard pain management can reduce the need for opioid painkillers and improve pain control after knee replacement surgery. 100 adult patients were randomly assigned to receive either standard care alone or standard care…

This study tested whether thread embedding acupuncture (placing a tiny thread under the skin at a specific back point) can reduce pain and improve quality of life after laparoscopic kidney donation surgery. 32 healthy kidney donors took part. Half received the real acupuncture pl…

This study tested two medicines, dexmedetomidine and lidocaine, given through an IV during mastectomy surgery to see which one controls pain better after the operation. Forty women having a modified radical mastectomy took part. The main goal was to see how long it took before th…

This study looked at 120 heart surgery patients to see which pain relief method works better: a nerve block near the breastbone or injecting pain medicine into the wound. Researchers measured pain levels and a natural painkiller in saliva to compare the two approaches. The goal w…

This study tested whether giving ibuprofen before hernia surgery helps older adults avoid temporary confusion and memory loss afterward. 76 men aged 65-84 received either ibuprofen or a placebo before surgery. Researchers measured thinking skills, pain levels, and recovery qualit…

This study looked at which pain medicine works better after major belly surgery: gabapentin or diclofenac sodium. 240 adults having elective abdominal surgery were given one of the two drugs. The goal was to see which kept pain scores low without needing extra pain relief. Result…

This study compared two ways of doing kidney stone surgery (PCNL). In the standard method, a tube is left in the kidney to drain urine, which can cause pain. In the tubeless method, no tube is placed. Researchers measured pain and painkiller use in 60 adults after surgery. The go…

This study looked at 40 infants under 1 year old having kidney surgery. They received a pain block with either bupivacaine alone or bupivacaine plus ketamine. The goal was to see if adding ketamine reduces pain and the need for extra pain medicine after surgery.

This study tested whether putting ice packs on the belly after a planned C-section could lower pain and the need for strong painkillers like opioids. Eighty women who had a C-section under spinal anesthesia took part. Half got standard pain care plus ice packs, and the other half…

This study looked at 200 adults having day surgery with general anesthesia to see if giving pain medication prescriptions before surgery (during the anesthesia check-up) reduces pain at home compared to giving the prescription after surgery. The main goal was to see how many peop…

This study tested whether doing progressive relaxation exercises after emergency general surgery could help with pain, anxiety, and vital signs like heart rate and breathing. Seventy adults were randomly assigned to either do these exercises at specific times after surgery or rec…

This study looked at 60 adults having lung surgery (VATS) to compare two pain-blocking techniques: Edge Laminar Block and Serratus Posterior Superior Intercostal Plane Block. The goal was to see which one better reduces pain, lowers the need for strong painkillers, and causes few…

This study looked at two different ultrasound-guided nerve blocks to manage pain after hip replacement surgery in people aged 65 and older. The goal was to see which block leads to better recovery quality, less pain, and fewer complications like confusion or nausea. 62 participan…

This study tested whether a nerve block in the nose could reduce pain after face surgery. Sixty adults were split into two groups: one received numbing medicine, the other salt water. Researchers measured pain levels and how much painkiller was needed during surgery.

This study tested a new painkiller called HTX-011 in 243 women having breast augmentation surgery. The drug was given as a nerve block before surgery to see if it could reduce pain and the need for opioid painkillers afterward. The goal was to improve recovery and lower the risk …

This study tested two types of ultrasound-guided nerve blocks to control pain after open total abdominal hysterectomy. 42 adults received either a transversus abdominis plane (TAP) block or an ilioinguinal-iliohypogastric (IIH) block. The goal was to see which block delayed the n…

This study tested a new long-acting painkiller called HTX-011 in 418 adults having hernia surgery. The goal was to see if it reduces pain and the need for opioid pain pills after the operation. Participants received either the study drug, a standard painkiller, or a placebo to co…

This study compared two types of nerve blocks (ESP block and QL block) to see which one controls pain better after abdominal surgery. 100 adults having surgery for cancers or gallbladder issues took part. The goal was to measure how much strong pain medicine they needed and their…

This study looked at whether a special nerve block, called an erector spinae plane block, can reduce pain after breast cancer surgery that includes implant reconstruction. One hundred women scheduled for this surgery took part. The goal was to see if the block lowers pain scores …

This study looked at whether adding a second nerve block (parasternal intercostal plane block) to a standard one (serratus anterior plane block) helps control pain after breast reduction surgery. 90 women were split into three groups: no block, one block, or both blocks. The main…

This study looked at 84 women having a diagnostic hysteroscopy, a procedure to look inside the uterus. Researchers compared spinal anesthesia (numbing the lower body) with general anesthesia (being fully asleep) to see which led to less pain and higher satisfaction. The goal was …

This study tested three experimental pain medicines (HTX-011, HTX-002, HTX-009) in 463 adults who had hernia surgery. The goal was to see how safe and effective they were at reducing pain after the operation. Participants received the medicine as a shot or on the skin, and report…

This study looked at ways to improve pain control after laparoscopic colorectal surgery. Researchers gave 120 adults a nerve block (erector spinae plane block) and added either ketamine or a fentanyl patch. The goal was to see which combination delayed the need for extra pain med…

This study tested whether spraying a mix of budesonide and lidocaine directly on the voice box (glottis) can reduce sore throat after thyroid surgery. 96 adults having thyroid surgery with nerve monitoring were randomly assigned to get either the drug spray or a saltwater spray. …

This study looked at whether letting children play with sand before a tonsillectomy helps lower their anxiety and pain. Sixty-eight kids aged 7 to 10 took part, with half doing sand play and half getting usual care. Researchers measured anxiety before surgery and pain afterward, …

This study tested three ways to manage pain during inguinal hernia repair: local anesthetic injection, quadratus lumborum block (QLB), and transversus abdominis plane (TAP) block. 90 adults having surgery under general anesthesia took part. Researchers measured recovery quality a…

This study tested three different doses of spinal morphine (50, 150, or 250 micrograms) to see which provides the longest pain relief after a C-section. 72 healthy women participated, and researchers measured how long until they needed extra pain medication. The goal is to improv…

This study tested whether a nerve block (suprazygomatic maxillary nerve block) can reduce pain and the need for strong painkillers in children after tonsillectomy and adenoidectomy. Researchers also added dexmedetomidine to see if it makes pain relief last longer. 114 children ag…

This study compared two types of nerve blocks (ESP and RIB) to see which one provides better pain relief after breast surgery. 84 patients received one of the blocks, and researchers measured how much morphine they needed and their pain scores. The goal was to find a more effecti…

This study tested whether a numbing injection in the neck (superficial cervical plexus block) before thyroid surgery could reduce pain and the need for strong painkillers like opioids. Forty adults having thyroid surgery under general anesthesia were split into two groups: one go…

This study tested whether a mix of low-dose ketamine and lidocaine works better than the opioid fentanyl for pain after gynecologic surgery. 70 adults having elective gynecologic surgery under general anesthesia took part. The goal was to see if the combo could reduce pain and si…

This study looked at 56 adults who had major abdominal surgery to compare two pain relief methods: a spinal injection of morphine and a newer nerve block technique. The goal was to see which method better reduces pain and the need for extra opioids, while causing fewer side effec…

This study tested whether a special nerve block (PENG block) given before partial hip replacement surgery could lower the amount of painkiller (tramadol) patients needed afterward. 48 adults aged 18-75 took part. Half got the block, half did not. Researchers measured pain scores …

This study looked at whether giving children a drug called dexmedetomidine during tonsillectomy and adenoidectomy surgery can prevent restlessness and reduce pain afterward. 85 children aged 2-10 years took part. Researchers measured pain and anxiety levels after the operation to…

This study looked at whether special nerve blocks (SAP and PECS) could help people recover faster after open-heart surgery compared to standard pain medicine. 243 adults having coronary artery bypass grafting were randomly assigned to one of three pain control methods. The main g…

This study looked at whether using absorbable tacks to fix mesh in laparoscopic hernia repair causes more pain than leaving the mesh unfixed. Sixty adults with a single inguinal hernia were randomly assigned to one of the two methods. Researchers measured pain, quality of life, a…

This study tested a new pain-relief drug called HTX 011 in 412 adults having bunion surgery. The drug was given as a shot into the surgical site to manage pain and reduce the need for opioid painkillers. Results showed it worked better than a placebo and a standard painkiller, he…

This study tested whether injecting a long-lasting numbing medicine (bupivacaine) into surgical sites just before waking up from anesthesia could reduce pain and the need for strong painkillers after jaw surgery. 102 adults having jaw surgery took part. Researchers measured pain …

This study tested two ways to manage pain after heart surgery: one using a single nerve block near the breastbone, and another adding a second block near the ribs. 72 adults having planned heart surgery took part. The goal was to see if the combined block reduced pain and helped …

This study tested a desensitizing gel (Teethmate Desensitizer) to see if it reduces tooth sensitivity after a filling. Fifty adults aged 18-65 with cavities received either the gel under their filling or a standard filling. They rated their pain using a scale from 0 to 10. The go…

This study looked at whether applying ice packs after hemorrhoid surgery can help manage pain. Researchers compared 429 patients who used ice packs to those who did not. The goal was to see if ice packs could lower pain scores and reduce the need for strong painkillers. Results s…

This study looked at 110 adults having keyhole lung surgery to see which pain relief method works best. Some patients got one of two ultrasound-guided nerve blocks, while others got standard pain medicine. The goal was to find which approach reduces pain and the need for strong p…

This study tested if a single session of light therapy, applied to the cheek right after removing an impacted wisdom tooth, could reduce pain, swelling, and jaw stiffness. 70 healthy adults took part. The light therapy helped lower pain in the first few days but did not reduce sw…

This study tested a new pain medicine called HTX 011 in 63 adults having hernia surgery. The goal was to see if it could help control pain and reduce the need for strong opioid painkillers. Researchers measured how many people needed no opioids after surgery and how much pain the…

This study looked at 70 children having chest surgery to see if a newer pain-block method (erector spinae plane block) works as well as the standard epidural. The goal was to control pain and keep the heart stable. The newer method may be safer and easier for children.

This study tested whether adding a special nerve block (called PENG block) to standard pain injections could better control pain after hip replacement surgery. 64 adults scheduled for hip replacement took part. The goal was to see if the nerve block reduces the need for morphine …

This study looked at whether using a special electronic device during a second root canal treatment can lower pain afterward. 144 adults with infected teeth were treated using different settings on the device. Pain was tracked for a week. The goal was to see if the device's setti…

This study tested whether giving a numbing injection around the eye before retinal surgery could lower pain, nausea, and a reflex that slows the heart during the operation. 184 adults having vitreoretinal surgery took part. Researchers compared three different numbing medicines t…

This study looked at whether taking ibuprofen for eight days after hip or knee replacement surgery is safe. Over 2,900 adults were followed for 90 days to track serious problems like heart attack, stroke, bleeding, or kidney failure. The goal was to help doctors decide if ibuprof…

This study tested two types of nerve blocks to control pain after total knee replacement. 62 patients received either a new para-sartorial block or a standard femoral-sciatic block. The goal was to see which provides better pain relief with less muscle weakness. Results will help…

This study tested whether putting lignocaine (a numbing medicine) inside the abdomen during gynecologic open surgery can reduce pain afterward. 112 women having surgery like hysterectomy or cystectomy took part. The goal was to see if this approach lowers pain scores and the need…

This study tested a new medicine called HTX-034 to see if it can control pain after bunion surgery better than the standard local anesthetic. 78 adults having bunion surgery received either HTX-034 or the standard treatment. The goal was to measure pain levels and safety over the…

This study compared two types of nerve blocks (TAP and QLB) to see which one better controls pain and reduces the need for strong painkillers after laparoscopic gallbladder removal. 65 adults having this surgery received one of the two blocks. The goal was to find a safer way to …

This study looked at 118 women having planned C-sections to compare two pain relief methods: a nerve block (quadratus lumborum block) and morphine given in the spinal anesthesia. The goal was to see which approach reduced the need for extra pain medicine in the first 24 hours aft…

This study tested whether giving the numbing drug lidocaine through a vein during liver surgery can help patients recover with less pain and less need for strong opioid painkillers. 124 adults having minor liver surgery took part, with half getting lidocaine and half getting a pl…

This study tested whether avoiding opioids during weight-loss surgery can still control pain effectively. Sixty adults with severe obesity were randomly assigned to receive either opioid-free or standard opioid anesthesia. Researchers measured pain levels, need for extra pain med…

This study tested whether showing patients a short video about moving after hip replacement surgery could reduce their fear of movement and pain. 96 adults scheduled for hip replacement were split into two groups: one got the usual verbal instructions, and the other also watched …

This study tested two types of nerve blocks to control pain after thyroid removal surgery. Forty adults were randomly assigned to receive either a cervical erector spinae plane block or a cervical plexus block. The goal was to see which method reduced the need for morphine and im…

This study looked at whether common anti-inflammatory drugs (NSAIDs) can control pain as well as a mild opioid (tramadol) after minimally invasive surgery. Thirty adults received one of three pain medicines before surgery. Researchers measured their pain levels in the recovery ro…

This study looked at whether a natural enzyme mouthwash (ORAL7) can improve healing, reduce pain, and help with mouth opening after removing impacted lower wisdom teeth. 58 adults used either ORAL7 or a standard antiseptic mouthwash for one week after surgery. Researchers measure…

This study looked at how much local anesthetic to use in a nerve block (called PENG block) to control pain after hip replacement surgery. 50 adults having hip surgery received different volumes of the block. The goal was to find the best dose to reduce pain, lower the need for pa…

This study looked at whether giving a single high dose of vitamin C through a vein, along with nerve blocks, could help reduce pain and soreness after total knee replacement surgery. 73 adults aged 50 to 80 took part. The goal was to see if this combination improves early recover…

This study looked at 120 people having gallbladder surgery to see if the position they are in during a nerve block affects their pain relief. Participants received the block lying on their side, on their stomach, or sitting up. The goal was to find which position leads to less pa…

This study looked at 60 women having planned C-sections to see whether a diclofenac shot in the muscle or a rectal suppository works better for pain relief. Both methods were given every 8 hours for the first day after surgery. The goal is to help doctors choose the most effectiv…

This study tested whether gargling with ketamine before tonsil surgery can reduce pain in children. 420 kids aged 4-12 either gargled ketamine or a placebo before their operation. Researchers measured pain levels, bleeding, and need for extra pain medicine after surgery. The goal…

This study looked at whether adding a numbing injection into the wound and a steroid medication during a planned C-section could lower the number of women experiencing severe pain after surgery. The researchers compared pain scores before and after making this change in 100 women…

This study tested whether numbing the chest wall with two types of nerve blocks (PECS and SAP) can reduce pain and the need for strong painkillers after coronary artery bypass surgery. 243 adults participated, and researchers measured pain levels, opioid use, time on a breathing …

This study tested a single dose of an experimental painkiller called HTX-011 given directly into the surgical site during bunionectomy. 78 adults having foot surgery received the drug to see if it could control pain and reduce the need for opioid painkillers. The goal was to impr…

This study tested two different ways to numb the arm and shoulder for pain relief after shoulder surgery. The goal was to see which method works better for pain and is less likely to temporarily paralyze the breathing muscle (diaphragm). Thirty adults having shoulder arthroscopy …

This study compared two pain medicines, nalbuphine and morphine, to see which works better and has fewer side effects for women recovering from laparoscopic myomectomy (surgery to remove uterine fibroids). 80 women took part, and their pain was measured using a 1-10 scale. The go…

This pilot study tested whether a nerve block called the serratus anterior plane (SAP) block can help control pain after heart surgery. 50 adults having heart surgery through a chest incision were randomly assigned to receive either a numbing medicine (ropivacaine) or a placebo t…

This study tested a nerve block (intertransverse process block) given before heart surgery to see if it reduces pain afterward. 76 adults having planned coronary artery bypass grafting took part. Half received the nerve block and half a placebo. The researchers measured pain scor…

This study tested whether combining two pain medications, duloxetine and pregabalin, can better control pain after liposuction compared to standard care. Ninety adults undergoing liposuction took part. The goal was to reduce the need for stronger opioids and improve recovery with…

This study tested two types of nerve blocks to control pain after hypospadias surgery in 60 children aged 1 to 6. One block targets the pudendal nerve, the other the dorsal penile nerve, both guided by ultrasound. Researchers measured pain levels and how long relief lasted to fin…

This study looked at whether adding a TAP block (a numbing injection in the belly wall) to standard pain medicine after a C-section helps wounds heal better and lowers stress. 105 women having planned C-sections took part. They were split into three groups: standard pain relief, …

This study looked at whether giving a common painkiller (IV paracetamol) before a total abdominal hysterectomy can lower the amount of morphine needed after surgery. Forty women aged 30-50 took part. The goal was to see if this simple step could reduce pain and reliance on strong…

This study tested a special stitching technique during C-sections to see if it reduces pain and helps women get out of bed sooner. 60 women having their first C-section took part. The new method aims to put less tension on the tissue, which may lead to less pain and faster recove…

This study tested whether placing a gel made from a patient's own blood (platelet-rich fibrin) into the tooth socket after wisdom tooth removal can reduce pain, swelling, and jaw stiffness. Thirty adults with two impacted wisdom teeth each had one socket treated with the gel and …

This study tested whether a single dose of S-ketamine, given during surgery, could lower the amount of morphine patients needed for pain in the first 24 hours after laparoscopic gynecologic surgery. 53 relatively healthy adults took part. The goal was to see if S-ketamine could i…

This study tested whether a short mindfulness lesson before inguinal hernia surgery helps adults feel less pain afterward. 68 people took part, and researchers measured their pain, fear of pain, and how much pain interfered with daily life. The goal was to see if this simple, dru…

This study tested whether using an EEG (brain-wave) monitor during general anesthesia could reduce confusion and pain after dental surgery in children. 92 kids aged 4-10 were split into two groups: one got standard anesthesia care, the other got extra EEG guidance. The goal was t…

This study tested three experimental pain-relief drugs (HTX-011, HTX-002, HTX-009) given locally during bunionectomy to reduce postoperative pain. 430 adults participated to see how well the drugs controlled pain over the first 24 hours after surgery. The goal was to find a safer…

This study tested whether using a combination of dexmedetomidine and lignocaine (opioid-free anesthesia) could control pain as well as standard fentanyl (opioid-based anesthesia) in 60 adults undergoing nasal surgeries like sinus surgery or septoplasty. The goal was to see if the…

This study tested whether a numbing injection (nerve block) given before thyroid surgery helps people feel better the day after. 160 adults having thyroid surgery were randomly assigned to get either the numbing medicine or a saltwater placebo. They filled out surveys about their…

This study looked at whether using a special laser (diode laser) after a common dental procedure called direct pulp capping can help reduce pain and tooth sensitivity. Fifty-six people with tooth decay that reached the nerve were treated. Half got standard care, and half got stan…

This study looked at whether a short talk with a mental health professional before kidney donation surgery could help donors feel less anxious, have more stable vital signs during surgery, and experience less pain afterward. 123 adult kidney donors took part. The goal was to see …

This study looked at 118 adults having lung surgery to see if giving a mix of lidocaine, ketamine, and magnesium during the operation helps lower pain and the need for strong painkillers like morphine afterward. Researchers measured how much morphine patients used in the first 24…

This study tested whether using different amounts of numbing medicine in a back muscle injection (erector spinae plane block) could reduce pain and the need for morphine after a hysterectomy. 80 women having the surgery took part. The goal was to find the best volume for safer, m…

This study tested two doses of morphine given during spinal anesthesia for planned C-sections to see which provides better pain relief with fewer side effects. 240 women were randomly assigned to receive either 75 or 100 micrograms of morphine. Researchers measured pain levels an…

This study tested whether adding a second nerve block (rectus sheath block) to the usual one (pectointercostal fascial plane block) could better control pain after heart surgery. 62 adults having elective heart surgery through a chest incision were randomly assigned to receive ei…

This study tested a new pain-relieving medicine called HTX-011 in 285 people having knee replacement surgery. The medicine was injected into the surgical area to see if it could reduce pain and the need for strong opioid painkillers. The goal was to find a safer, more effective w…

This study tested if using a sonic device to clean the tooth during a root canal on baby molars reduces pain afterward. Thirty children aged 5-8 took part. Researchers also used an AI phone app to analyze children's facial expressions and compared it to a standard pain scale. The…

This study looked at 90 adults having laparoscopic hernia repair to compare two types of nerve blocks for pain after surgery. One block targets nerves near the ribs (M-TAPA) and the other targets nerves under the ribs (OSTAP). The goal was to see which block reduces pain and the …

This study followed 1,000 children aged 1-17 in Sweden who had common surgeries like hernia repair or tonsil removal. Researchers wanted to see how many children experience pain after surgery and whether doctors follow European pain management guidelines. The goal is to improve p…

This study looked at 120 women having mastectomy for breast cancer to see if the gender of their anesthesiologist affected their pain and need for painkillers after surgery. Researchers compared pain scores and medication use between patients treated by male versus female anesthe…

This completed study looked at how sleep apnea and other health problems like diabetes and high blood pressure affect pain after root canal treatment. 78 adults were divided into three groups: those with sleep apnea, those with diabetes or high blood pressure, and healthy people.…

This study looked at 114 children aged 2 to 7 having urogenital surgery to see if being anxious before the operation leads to more pain or confusion after. Researchers measured anxiety just before anesthesia and then tracked pain, delirium, and recovery in the recovery room. The …

This study looked at how patients felt about a common gum surgery called free gingival graft, at least one year after the procedure. Researchers surveyed 77 people to learn about their pain, satisfaction, and whether they would have the surgery again. The goal was to understand t…

This study looked at whether parents' confidence in letting their child be independent affects how much pain children feel after minor surgery. About 150 children aged 3 to 18 and their parents took part at a hospital in Turkey. Parents filled out questionnaires, and children's p…

This study followed 294 knee replacement patients to see how often they experienced a sudden, severe return of pain after their nerve block wore off. Researchers measured pain levels, sleep quality, and patient satisfaction. The goal was to better understand this 'rebound pain' t…

This study looked at 120 adults having shoulder surgery to see if feeling a tingling or electric shock during a nerve block injection leads to numbness, weakness, or pain afterward. Researchers noted when the sensation happened and then checked patients by phone after the block w…

This study looked at 72 adults with infected tooth roots to see if the type of filler used during root canal treatment changes how much pain they feel and how well the bone heals. Patients got one of three common fillers, and their pain was checked right after, at 24 hours, and a…

This study looked at how well standard pain treatments work for children after planned surgeries. Researchers watched 219 kids aged 0-18 during their first hour after surgery, using special pain scales for different ages. They recorded pain scores and any extra pain medicine need…

This study looked at how patients feel about nurses checking their pain after planned surgery. Researchers surveyed 312 adults to understand if monitoring feels supportive or stressful and how it affects trust and pain reporting. No treatments were tested; the goal was to learn a…

This study looked at how satisfied patients were with their pain control after outpatient ear, nose, and throat surgery. Researchers compared those who received opioid painkillers to those who received non-opioid options. The goal was to see if non-opioid treatments could provide…

This study looked back at the records of 489 adults who had Achilles tendon surgery to find out what factors lead to moderate-to-severe pain in the first 24 hours after the operation. The researchers created a simple tool (called a nomogram) to help doctors predict which patients…

This study looked at how psychological factors like self-esteem and personality traits influence pain after cosmetic breast surgery. Researchers followed 52 adults to see if these factors could predict pain levels and recovery. The goal is to help doctors create more personalized…

This study looked at how ketorolac, a non-steroidal anti-inflammatory drug (NSAID) used for pain after cesarean delivery, affects platelet function and blood clotting. Researchers measured clotting in 40 women undergoing scheduled C-sections using special blood tests. The goal wa…

This study tracked 200 adults who had chest surgery (sternotomy) to see how many still had pain three months later. Researchers asked about pain levels and how it affected daily life. The goal was to learn how common long-term pain is and what might make it more likely.