Nalbuphine vs morphine: which painkiller wins for Post-Surgery relief?

NCT ID NCT03288428

Completed Symptom relief Sponsor: Peking University First Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two painkillers, nalbuphine and morphine, given through a patient-controlled pump to women recovering from laparoscopic myomectomy (surgery to remove uterine fibroids). The goal was to see which drug provides better pain relief and causes fewer side effects. Eighty women took part, and the study is already complete.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: nalbuphine and morphine
What this could lead to: If nalbuphine works as well as morphine with fewer side effects, it could become a preferred painkiller for women recovering from this surgery.
What could go wrong: This is a small, completed trial with only 80 participants, so results may not apply to everyone. Differences between the drugs might be small or not meaningful in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTOPERATIVE PAIN

Contacts and locations

Locations

First hospital Peking University

Beijing, Beijing Municipality, China

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