New shot may slash pain and opioid use after hernia surgery

NCT ID NCT03237481

First seen Mar 07, 2026 · Last updated Apr 30, 2026 · Updated 5 times

Summary

This study tested a new long-acting painkiller called HTX-011 in 418 adults having hernia surgery. The goal was to see if it could control pain and reduce the need for opioid painkillers after the operation. Participants received either HTX-011, a standard painkiller, or a placebo injected into the surgical site, and pain levels were tracked for 72 hours.

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Contacts and locations

Locations

  • Alliance Research Centers

    Laguna Hills, California, 92653, United States

  • American Institute of Research

    Whittier, California, 90603, United States

  • Anaheim Clinical Trials, LLC

    Anaheim, California, 92801, United States

  • Arizona Research Center

    Phoenix, Arizona, 85053, United States

  • Cornerstone Research Institute, LLC

    Longwood, Florida, 32750, United States

  • EPIC Medical Research, LLC

    Murray, Utah, 84123, United States

  • Eliza Coffee Memorial Hospital

    Florence, Alabama, 35630, United States

  • Endeavor Clinical Trials, P.A.

    San Antonio, Texas, 78229, United States

  • HD Research Corp

    Riverside, California, 92503, United States

  • Hermann Drive Surgical Hospital

    Houston, Texas, 77004, United States

  • Jean Brown Research

    Salt Lake City, Utah, 84124, United States

  • Jessa Ziekenhuis

    Hasselt, Limburg, 3500, Belgium

  • Lotus Clinical Research, LLC

    Pasadena, California, 91105, United States

  • Midwest Clinical Research

    Dayton, Ohio, 45417, United States

  • Park Place Surgery Center

    Maitland, Florida, 32751, United States

  • Plano Surgical Hospital

    Plano, Texas, 75093, United States

  • Shoals Medical Trials, Inc.

    Sheffield, Alabama, 35660, United States

  • St. Louis Clinical Trials

    St Louis, Missouri, 63141, United States

  • Trovare Clinical Research, Inc.

    Bakersfield, California, 93301, United States

  • University of Miami

    Miami, Florida, 33136, United States

  • Westside Surgical Hospital

    Houston, Texas, 77027, United States

  • Yale University School of Medicine

    New Haven, Connecticut, 06511, United States

  • Ziekenhuis Oost Limburg

    Genk, 3600, Belgium

  • eStudySite

    Las Vegas, Nevada, 89109, United States

Conditions

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