Ketamine gargle: a simple trick to ease Kids' pain after tonsillectomy?

NCT ID NCT07558044

Completed Symptom relief Sponsor: Hospital Universitario de Caracas Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether having children gargle with a ketamine solution just before tonsillectomy surgery could reduce their pain afterward. 420 children aged 4 to 12 years participated, with half receiving the ketamine gargle and half a placebo (salt water). The researchers measured pain levels and any complications in the first 24 hours after surgery to see if this simple, low-cost approach works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ketamine gargle
What this could lead to: If it works, this could offer a simple, low-cost way to reduce pain after tonsillectomy in children, potentially reducing the need for stronger painkillers.
What could go wrong: This is a single completed study. The results may not apply to all children or settings, and ketamine can cause side effects like dizziness or nausea.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADENOTONSILLECTOMY POSTOPERATIVE PAIN TONSILLECTOMY

Contacts and locations

Locations

VERAZA

Caracas, Miranda, 1040, Venezuela

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