Ketamine infusion may cut opioid use after knee surgery

This study looked at whether adding a ketamine infusion to standard pain management can reduce the need for opioid painkillers and improve pain control after knee replacement surgery. 100 adult patients were randomly assigned to receive either standard care alone or standard care plus a continuous ketamine infusion. Researchers measured pain levels and opioid use during the first 24 hours after surgery, as well as side effects like nausea and vomiting.