Ketamine may cut opioid use after knee surgery, study finds

NCT ID NCT07059429

First seen Oct 31, 2025 · Last updated May 01, 2026 · Updated 24 times

Summary

This study looked at whether adding a continuous infusion of ketamine to standard pain management can help people who had knee replacement surgery use fewer opioids and feel less pain. 100 adults were split into two groups: one got standard care plus ketamine, the other got standard care alone. Researchers measured pain levels and opioid use in the first 24 hours after surgery to see if ketamine made a difference.

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Contacts and locations

Locations

  • Pirogov National Medical and Surgical Center

    Moscow, 105203, Russia

Conditions

Explore the condition pages connected to this study.