Nerve block after C-Section may speed healing and lower stress

NCT ID NCT05840406

Completed Symptom relief Sponsor: University Hospital Sestre Milosrdnice Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether adding a TAP block (a type of nerve block) to standard pain relief after a cesarean section could improve wound healing and reduce stress on the body. 105 women having planned C-sections were randomly assigned to receive either standard pain medication alone, or standard medication plus a TAP block with levobupivacaine, or a TAP block with levobupivacaine and dexmedetomidine. Researchers measured wound healing, stress hormones, and immune markers in the days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: levobupivacaine and dexmedetomidine
What this could lead to: If it works, this could lead to better pain control and faster wound healing after cesarean delivery.
What could go wrong: This is a small, completed study with no phase designation, so results may not apply broadly. The benefits over standard pain management may be modest.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CESAREAN SECTION POSTOPERATIVE PAIN WOUND HEAL

Contacts and locations

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Locations

University Hospital Center Sestre milosrdnice

Zagreb, 10000, Croatia

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