POSTOPERATIVE PAIN

This study looks at two different places to inject numbing medicine for a knee nerve block in 68 people having knee replacement surgery. The goal is to see which injection spot works better to control pain and reduce the risk of falls after surgery. Researchers will measure how f…

This study tests a recovery plan called ERAS in 60 adults getting a kidney from a living donor. The plan includes a pre-surgery drink, Tylenol, gabapentin, a numbing injection during surgery, and early walking. The goal is to see if it lowers pain and the need for strong narcotic…

This study tests whether adding two medications (dexamethasone and dexmedetomidine) to a standard nerve block can extend pain relief and reduce the need for opioid painkillers after shoulder, foot, or ankle surgery. About 100 adults will be randomly assigned to receive either the…

This study tests whether an automated pupillometer—a device that measures how the pupil reacts to light—can help doctors better assess and treat pain during and after surgery. 68 adults having abdominal surgery will be randomly assigned to either standard pain care or care guided…

This study looks at two types of ultrasound-guided nerve blocks (TAP and QLB) to manage pain after open inguinal hernia repair. 70 adults aged 18-65 will receive one of the blocks before surgery, and their pain levels and need for extra painkillers will be tracked for 24 hours. T…

This study tests whether an ultrasound-guided nerve block (superficial cervical plexus block) given before neck surgery can lower pain after the operation and reduce the need for opioid painkillers. Sixty adults aged 18-60 having elective neck surgery under general anesthesia wil…

This study tests whether a single injection of dexamethasone, a steroid, can reduce pain after surgical removal of impacted wisdom teeth. 70 adults aged 20-40 will be split into two groups: one gets standard numbing medicine, the other gets an extra steroid shot after surgery. Pa…

This study looks at two different nerve blocks—pericapsular nerve block and anterior quadratus lumborum block—to see which one works better for reducing pain when patients are positioned for spinal anesthesia and after hip fracture surgery. About 64 adults aged 30 to 85 will take…

This study aimed to see if injecting a long-lasting painkiller (Exparel) into the vaginal cuff before a minimally invasive hysterectomy could lower pain after surgery. It planned to compare the painkiller mixed with a standard numbing drug versus the standard drug alone. The stud…

This study looks at whether a special nerve block (serratus posterior superior intercostal plane block) can reduce pain and the need for painkillers after cervical disc herniation surgery. About 40 adults having this neck surgery will be divided into groups to compare the nerve b…

This study tests two medicines, dexmedetomidine and tramadol, given before hemorrhoid surgery to see which one better reduces anxiety and pain. About 90 adults having the surgery will receive one of the drugs or a placebo. Researchers will measure anxiety levels, pain scores, and…

This study tests if a nerve block (serratus intercostal plane block) works better than the usual method (port infiltration) for pain after laparoscopic gallbladder removal. 128 adults having this surgery will be randomly assigned to one of the two pain treatments. The goal is to …

This study tested whether a single dose of long-acting corticosteroids given before wisdom tooth removal can reduce pain, facial swelling, and trouble opening the mouth after surgery. Sixty adults aged 18 to 35 were randomly assigned to receive either the steroid or a placebo bef…

This study looks at whether a special nerve block (called ESPB) can help control pain after surgery for a slipped disc in the lower back. About 78 adults having this surgery will receive the block, and researchers will measure their pain levels, how much pain medicine they need, …

This study tests whether giving certain pain medications during nose surgery can reduce the number of strong opiate pills needed afterward. About 50 adults having nose surgery will be randomly assigned to receive either the extra medications or standard care. The goal is to see i…

This study aimed to see if taking oral steroids after nose surgery (rhinoplasty) could reduce pain, nausea, swelling, and bruising. It was designed for adults having their first nose surgery, but the study was withdrawn before any participants were enrolled. No results are availa…

This study compares two types of nerve blocks (serratus plane block and rhomboid intercostal plane block) to see which provides better pain relief after breast reduction surgery. About 90 women will receive one of the blocks before surgery, and their pain and opioid use will be t…

This study tests two ways to numb the area for collarbone surgery. One method (SCB-CPB) aims to provide good pain relief with fewer breathing side effects than the standard technique (SCB-ISB). 34 adults having collarbone surgery will be randomly assigned to one of the two nerve …

This study planned to compare a less invasive version of open hemorrhoid surgery with the standard surgery in adults with grade III hemorrhoids. The goal was to see if the gentler approach leads to less pain after the operation. However, the study was withdrawn before any partici…

This study tests whether giving no opioids after inguinal hernia repair works as well as giving a few opioid pills. About 900 adults having routine hernia surgery will be randomly assigned to receive either no opioid prescription or a small supply (5 tablets). The main goal is to…

This study looks at whether showing children a video before their tonsil surgery can reduce their fear, anxiety, and pain. 60 children aged 4-10 who are having their first surgery will watch an educational video. Their fear, anxiety, and pain levels will be measured before and af…

This study tests whether a specific nerve block (erector spinae plane block) can lower the need for strong painkillers after open abdominal surgery. About 46 adults having abdominal surgery under general anesthesia will receive the block or standard care. The goal is to see if fe…

This study compares two types of nerve blocks (quadratus lumborum block and retrolaminar block) to see which one works better for pain after lumbar disc herniation surgery. About 84 adults having elective back surgery will be enrolled. The goal is to find which block reduces pain…

This study compares two types of nerve blocks—Subcostal Transversus Abdominis Plane Block and Rectus Sheath Block—to see which one better controls pain after abdominal surgery. Sixty adults having a midline incision laparotomy will be enrolled. Researchers will measure pain score…

This study looks at whether adding flurbiprofen axetil to a standard numbing medicine (ropivacaine) injected into the scalp before brain surgery can lower pain and the need for strong painkillers afterward. About 216 adults having brain surgery will take part. The goal is to see …

This study compares two types of nerve blocks to manage pain after abdominal surgery. Sixty adults having surgery through a midline belly cut will receive either a modified thoracoabdominal nerve block or a rectus sheath block. The goal is to see which method reduces pain scores …

This study compares two types of nerve blocks to manage pain after arthroscopic shoulder surgery. The goal is to find which block provides better pain relief while reducing the risk of temporary diaphragm paralysis, a common side effect. Thirty adults having shoulder surgery will…

This study looks at two ways to manage pain after gynecologic surgery: the EXORA block and epidural analgesia. Researchers want to see which method helps patients recover better and feel less pain. Sixty adults having elective gynecologic surgery will take part, and their recover…

This study looks at how a painkiller called remifentanil changes a person's pain threshold before surgery. About 40 adults will have their pain threshold measured using a device that applies pressure. The goal is to understand the relationship between drug dose and pain sensitivi…

This study looks at whether a child's genes can predict how they will respond to morphine after tonsil surgery. The goal is to find out which children are likely to have severe side effects or poor pain relief. 1,200 children aged 3-15 are being studied to help doctors personaliz…

This study tracks 300 adults who receive light therapy as part of their standard care after elective plastic surgery. Researchers will measure pain, swelling, bruising, and patient satisfaction over time. The goal is to describe recovery patterns, not to test a new treatment.

This study looks at whether certain signs of inflammation in the blood can predict if numbing shots for dental work will work well and how much pain people feel afterward. About 150 adults with tooth pain will have their blood tested and their anesthesia success tracked. The goal…