Could a simple injection slash opioid use after nose jobs?

NCT ID NCT06989866

ENROLLING_BY_INVITATION Symptom relief Sponsor: United States Naval Medical Center, Portsmouth Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a numbing medicine called bupivacaine, injected after nose surgery, can reduce the need for strong opioid pain pills. Fifty adults having septorhinoplasty will receive either the numbing injection or a placebo. Researchers will count how many opioid pills they use and track their pain levels for a week.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Bupivacaine (a numbing medicine injected after surgery)
What this could lead to: If it works, this could offer a way to control pain after nose surgery with fewer opioid pills, reducing the risk of dependence.
What could go wrong: This is a small, early-phase trial with only 50 participants, so results may not apply to everyone. The numbing effect may not be strong enough to replace opioids for all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTOPERATIVE PAIN

Contacts and locations

Locations

Naval Medical Center Portsmouth

Portsmouth, Virginia, 23708, United States

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