Could a natural enzyme mouthwash replace harsh antiseptics after wisdom tooth surgery?

NCT ID NCT07627945

First seen Jun 25, 2026 · Last updated Jul 02, 2026 · Updated 3 times

Summary

This study tested whether a natural enzyme-containing mouthwash (ORAL7) helps wounds heal better and reduces pain after impacted wisdom tooth removal, compared to a standard antiseptic mouthwash. 58 adults used either the enzyme mouthwash or chlorhexidine mouthwash for one week after surgery. Researchers measured wound healing, pain levels, and mouth opening to see if the natural option works as well or better with fewer side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ORAL7® mouthwash (contains lactoperoxidase, lysozyme, lactoferrin, glucose oxidase)
What this could lead to
If it works, this could offer a gentler alternative to standard antiseptic mouthwash for recovery after wisdom tooth surgery, with fewer side effects like staining or taste changes.
What could go wrong
This is a small, completed trial with only 58 participants. The results may not apply to everyone, and the natural mouthwash may not be more effective than the standard one.

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Conditions

The condition(s) this trial relates to.

injury Pain, Postoperative Trismus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Oral and Maxillofacial Surgery Unit, School of Dental Sciences, Universiti Sains Malaysia

    Kota Bharu, Kelantan, 16150, Malaysia

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