New rinse may ease root canal pain better than standard
NCT ID NCT07173725
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether a rinse called octenidine reduces pain after root canal treatment better than the standard rinse chlorhexidine. 142 adults with a single-rooted tooth and asymptomatic apical periodontitis received one of the two rinses during their procedure. Pain was recorded at 6, 12, 24, and 48 hours after treatment. The goal was to see if octenidine leads to less early pain.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Octenidine dihydrochloride 0.1% solution
What this could lead to
If octenidine works better, it could offer a new option to reduce pain after root canal treatment.
What could go wrong
This is a small, completed trial comparing two rinses, not a new treatment. Results may not apply to all teeth or pain types.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Bezmialem Vakif University Dental Hospital - Department of Endodontics
Istanbul, 34093, Turkey (Türkiye)