DIABETES MELLITUS TYPE 2

This study tested a new insulin dosing calculator for adults with type 2 diabetes when they are admitted to the hospital. The goal was to see if the calculator could help keep blood sugar levels from getting too high or too low without causing dangerous drops. 38 participants rec…

This 16-week study tested whether a low-fat vegan diet can improve insulin sensitivity and blood sugar control in people with type 2 diabetes. Twenty-six adults with type 2 diabetes and a BMI between 26 and 40 participated. They received weekly nutrition classes and one-on-one di…

This study looked at whether a heart-healthy DASH diet, modified for people with type 2 diabetes, along with less salt, can lower blood pressure. 105 adults with diabetes and high blood pressure were given different diets for five weeks each. The goal was to see if the DASH diet …

This study looked at how the diabetes pill Rybelsus (oral semaglutide) works in real-world settings for adults with type 2 diabetes. About 194 participants took the medication as prescribed by their doctor and completed questionnaires over 8-10 months. The main goal was to see if…

This study tested whether personalized text messages can help people with type 2 diabetes take their daily pills more consistently. 28 adults who had trouble sticking to their medication schedule received either tailored or generic text messages for 6 months. The goal was to see …

This study looked at how safe and effective Xultophy is for adults with type 2 diabetes when used in normal doctor visits. About 750 people took the medicine as their doctor prescribed for 26 weeks. The goal was to track side effects and changes in blood sugar and weight.

This study looked at three different diabetes medicines (empagliflozin with metformin, sitagliptin with metformin, or metformin alone) in 186 adults who were newly diagnosed with type 2 diabetes and overweight. Over 12 weeks, researchers measured changes in blood markers, blood s…

This study tested a new insulin called icodec that is injected just once a week, compared to a standard daily insulin (degludec), in 526 adults with type 2 diabetes. The goal was to see if the weekly insulin controls blood sugar as well as the daily one over 26 weeks. Participant…

This study tested a new once-weekly medicine called IcoSema (a mix of two diabetes drugs) against daily insulin shots in 679 adults with type 2 diabetes whose blood sugar was not well controlled. The goal was to see if the weekly shot works as well as daily insulin for lowering b…

This study looked at how safe and effective Fiasp® insulin is for people with type 1 or type 2 diabetes. It involved 42 adults who used the insulin as their doctor prescribed. The study lasted about 6 months and tracked side effects and blood sugar control.

This study tested if weight-loss surgery (vertical sleeve gastrectomy) could improve pancreas, kidney, and heart health in teens aged 12-21 with type 2 diabetes and severe obesity. Researchers measured kidney function, blood flow, and insulin production before and after surgery. …

This study followed 50 adults with type 2 diabetes in Finland who were prescribed oral semaglutide (Rybelsus) by their doctor. The goal was to see how well the medication lowers blood sugar levels over 8-10 months. Participants completed a questionnaire about how they took their …

This study tested whether dapagliflozin, a drug used for diabetes, can improve heart structure in people with kidney failure who are on dialysis. Researchers compared the drug to a placebo in 220 adults. The goal was to see if it could reduce heart muscle thickening, a common pro…

This study followed 194 adults with type 2 diabetes in Sweden who were prescribed oral semaglutide (Rybelsus) by their own doctors. Researchers tracked changes in blood sugar levels and body weight over 8-10 months. Participants also filled out questionnaires about how they took …

This study tested a new investigational medicine called CagriSema, which combines two drugs (cagrilintide and semaglutide), in 158 adults with type 2 diabetes. Participants received either CagriSema, one of the drugs alone, or a placebo, all alongside their usual metformin. The g…

This study looked at whether taking probiotics alongside usual diabetes medications can improve blood sugar, cholesterol, and inflammation in adults with type 2 diabetes. 77 participants aged 35-65 took probiotics or a placebo. The goal was to see if changing gut bacteria could h…

This study tested a new once-weekly injection called IcoSema, which combines insulin and another diabetes drug, against once-weekly insulin alone in over 1,200 adults with type 2 diabetes. The goal was to see which better controls blood sugar over a year. Participants were random…

This study tested whether treating binge eating disorder (BED) can also improve type 2 diabetes and heart health. Thirty-four adults with both conditions received psychotherapy for BED. Researchers measured changes in binge eating episodes and diabetes severity before and after t…

This study tested whether adding a new experimental medicine (NNC0480-0389) to the existing diabetes drug semaglutide can better control blood sugar in people with type 2 diabetes. About 500 adults took weekly injections for 41 weeks. The goal was to find the best doses for futur…

This study looked at how well the diabetes pill Rybelsus works in everyday life for adults with type 2 diabetes in Saudi Arabia. About 194 participants took the medication as prescribed by their doctor and completed questionnaires during regular visits. The main goal was to see i…

This study tested whether a once-weekly injection of semaglutide (a diabetes drug) plus a lower dose of insulin works as well as a higher dose of insulin alone for controlling blood sugar. About 573 adults with type 2 diabetes and overweight took part. The goal was to see if the …

This study checked how safe Lyumjev, a rapid-acting insulin, is for adults with type 2 diabetes in India. About 150 people who already use daily insulin injections took part for 26 weeks. Researchers tracked low blood sugar episodes to see if the drug is safe for ongoing diabetes…

This study tested a high dose (7.2 mg) of semaglutide, a once-weekly injection, in 512 adults with obesity and type 2 diabetes. The goal was to see how much weight participants lost and how well their blood sugar was controlled over 72 weeks, compared to a lower dose or a placebo…

This study tested whether simple foot exercises could improve blood flow in the legs of people with type 2 diabetes. 44 adults did either foot exercises or regular activity for 3 months. Those who did the foot exercises had better circulation, showing this is a low-cost way to he…

This study followed 458 adults with type 2 diabetes in Italy who were already prescribed oral semaglutide (Rybelsus) by their doctor. Researchers tracked changes in blood sugar levels and body weight over about 8-10 months. The goal was to see how well the medication works in rea…

This study tested a virtual health program for African immigrants aged 25-75 who are uninsured and have at least two risk factors like high blood pressure, prediabetes, or obesity. Participants used Bluetooth scales and blood pressure monitors to track their health over six month…

This study tested whether a smartphone app that uses artificial intelligence (AI) and game-like features can help people with type 2 diabetes better manage their blood sugar. The app provided personalized health coaching and was designed to work even in rural areas with limited p…

This study tested a remote program that combines digital tools with a 12-week very low-calorie diet (800 calories per day) to help adults with type 2 diabetes lose weight and possibly achieve remission. 100 participants were randomly assigned to either the program or standard car…

This study tested whether taking a higher dose (25 mg or 50 mg) of the once-daily diabetes pill semaglutide works better than the standard 14 mg dose. Over 1,600 adults with type 2 diabetes took part, gradually increasing their dose over 68 weeks. The main goals were to see if th…

This study looked at whether taking vitamin D3 and prebiotics (a type of fiber) every day for 6 months could improve heart health in adults with type 2 diabetes. 190 people participated. The researchers measured changes in blood sugar, cholesterol, and gut bacteria. The goal was …

This study looked at whether using a smartphone app called 'Dose Check' together with the insulin Tresiba helps people with type 2 diabetes control their blood sugar. About 179 adults in Saudi Arabia took part for 6-7 months. The main goal was to see if their average blood sugar …

This study looked at whether a nutritional drink called Resource Diabet Plus can help people with type 2 diabetes who are also malnourished or at risk of malnutrition. Researchers reviewed medical records of 59 patients in Spain who took the drink for at least 24 weeks. The goal …

This study looked at whether delivering healthy food to the homes of people with type 2 diabetes who live in rural areas and struggle to afford food can help them manage their condition better. Over 400 adults took part, receiving either standard care alone or standard care plus …

This study tested whether using mobile monitoring devices along with nurse support can help people better manage type 2 diabetes and high blood pressure. 220 adults with poorly controlled diabetes and high blood pressure took part. Researchers measured changes in blood sugar and …

This study looked at how quickly a new fast-acting insulin (faster aspart) enters the blood compared to a standard insulin (NovoRapid) in 23 Chinese adults with type 1 or type 2 diabetes. Each participant received one injection of each insulin on separate visits, and blood sample…

This early study tested a new medicine, NNC0519-0130, given as a weekly shot to help with weight loss and blood sugar control. 82 adults with obesity or type 2 diabetes took part. The main goal was to check for side effects and see how the drug works in the body, with a focus on …

This study tested whether combining two medicines, cagrilintide and semaglutide, works better than either alone for controlling blood sugar in people with type 2 diabetes. 92 adults received either the combo or a single drug plus a dummy shot for about 32 weeks. The main goal was…

This study tested a new diabetes pill (semaglutide) against a dummy pill in 132 children and teens with type 2 diabetes. Participants took one tablet each morning on an empty stomach and waited 30 minutes before eating. The study lasted about 15 months and checked how well the me…

This study tested a new medicine called survodutide (BI 456906) in 755 adults with overweight or obesity and type 2 diabetes. Participants received weekly injections of either the drug or a placebo for 76 weeks, along with diet and exercise advice. The main goals were to see how …

This study looked at whether adding dapagliflozin to metformin helps people with severe obesity (BMI 40+) and prediabetes or type 2 diabetes lose more weight than metformin alone. Over 12 months, researchers measured weight, blood pressure, and waist changes. The goal was to see …

This study followed 291 adults with type 2 diabetes whose blood sugar was not well controlled on their current medication (DPP4i). Participants switched to an oral medication called semaglutide and were monitored for about 5-6 months. Researchers measured changes in blood sugar l…

This study looked at how well the diabetes pill Rybelsus (oral semaglutide) works in real-world settings for adults with type 2 diabetes. Researchers tracked changes in blood sugar levels and body weight over about 8-10 months. Participants took the medication as prescribed by th…

This study tested a new insulin that is injected just once a week against a standard daily insulin in 582 adults with type 2 diabetes. The goal was to see if the weekly insulin controls blood sugar as well as the daily one. Participants also used mealtime insulin. The trial laste…

This study tested a new once-weekly insulin (icodec) combined with a flash glucose monitor (a small sensor worn on the arm) in 51 adults with type 2 diabetes who had never used insulin before. The goal was to see if this approach helps control blood sugar levels over 26 weeks. Pa…

This study tested whether a dietary supplement called phosphatidylserine (PS) can improve blood flow and insulin response in people with type 2 diabetes. Thirty-six adults aged 45-64 with type 2 diabetes took PS to see if it helps blood vessels work better. The goal is to find a …

This study tested two types of exercise in 50 adults with type 2 diabetes over 6 weeks. One group did circuit training (mixing aerobic and resistance exercises), and the other did standard strength training. Researchers measured heart and lung fitness, blood sugar, and quality of…

This study looked at whether providing specially prepared meals and nutrition counseling through video calls can help people with poorly controlled type 2 diabetes lower their blood sugar. About 600 adults with high A1C levels took part. The goal was to see if these services, del…

This study followed 155 adults with type 2 diabetes who were prescribed Rybelsus (oral semaglutide) by their doctors. The goal was to see how well the once-daily pill lowers blood sugar and affects body weight over 8-10 months. Participants completed a questionnaire about how the…

This study tested a smart system that helps people with type 2 diabetes decide how much insulin to take. 140 adults starting insulin therapy used either the smart system or standard care for 12 weeks. The goal was to see if the system improved blood sugar levels without increasin…

This study tested whether giving adults with type 2 diabetes who can't afford healthy food a special prescription for free or discounted groceries helps lower their blood sugar. About 600 people took part. The program aimed to make healthy eating easier and improve diabetes manag…

This study tested a new way to manage type 2 diabetes for patients at a primary care clinic serving vulnerable populations. The clinic offered dedicated diabetes care days, continuous glucose monitoring, and help with social needs like food and housing. Researchers tracked change…

This study looked at whether taking a probiotic supplement can improve blood vessel function and reduce inflammation in people with heart disease or type 2 diabetes. Researchers measured blood markers, gut bacteria, and vessel health in 215 adults. The goal was to see if changing…

This study tested a web-based version of a problem-solving program called eDECIDE for African Americans with type 2 diabetes. The program helps people manage daily challenges of living with diabetes. Researchers compared the online program to the traditional in-person version in …

This study tested whether people with type 2 diabetes and early kidney disease can manage their medications from home. Twelve participants took empagliflozin and, if needed, added finerenone to lower protein in their urine. They measured their own blood pressure, weight, and coll…

This study looked at the long-term safety and effectiveness of Ozempic in over 3,200 Japanese adults with type 2 diabetes. Participants took the drug as prescribed by their doctor for about 3 years. Researchers tracked side effects, blood sugar control, weight changes, and qualit…

This study looked at how well the once-daily pill Rybelsus® works for adults with type 2 diabetes in everyday life. Researchers tracked changes in blood sugar and body weight over about 8-10 months. Participants took the medication as prescribed by their doctor and filled out que…

This study looked at whether adding community health workers to regular care helps patients with type 2 diabetes and high blood pressure in rural Mexico. 168 adults took part. The goal was to see if their blood sugar and blood pressure improved and if they took their daily medici…

This study tested a new medicine, NNC0519-0130, in 299 adults with type 2 diabetes. Participants received weekly injections of different doses to see how well it lowers blood sugar and body weight. The study lasted about 40 weeks and is now complete.

This study tested a weekly injection of semaglutide (2.4 mg) to help people with overweight or obesity lose weight. 375 adults took part, some receiving the drug and others a placebo, along with lifestyle counseling. The main goal was to see how much weight they lost over 44 week…

This study tested whether taking lotus seed capsules can improve nerve function, blood sugar control, and immune health in people with type 2 diabetes who have nerve damage in their hands and feet. Sixty adults took either a placebo or lotus seed capsules along with their regular…

This study looked at three ways to help older adults (65+) with type 2 diabetes improve their body composition and physical function: circuit resistance training (home exercises), a plant-based Mediterranean diet, or the drug empagliflozin. One hundred participants were assigned …

This early study tested a new device used during an endoscopy to regenerate the lining of the small intestine in people with type 2 diabetes. Twenty adults whose blood sugar was not well controlled with 2-3 non-insulin medications took part. The main goal was to see if the proced…

This study tested a once-daily pill called RYBELSUS® against other diabetes pills in over 1,000 adults with type 2 diabetes who were already taking metformin. The goal was to see which pill works better at lowering blood sugar over one year. Participants were randomly assigned to…

This study tested a new fast-acting insulin (faster aspart) against a standard insulin (NovoRapid) in 331 adults with type 1 or type 2 diabetes. Both insulins were taken alongside a long-acting insulin, with or without metformin. The goal was to see if the new insulin works bette…

This study tested a new type of education for people with type 2 diabetes. Instead of just giving instructions, the program focused on empowering patients to manage their own condition. 50 adults with diabetes took part, and researchers measured their blood sugar control and self…

This study tested three different doses of semaglutide (2 mg, 8 mg, and 16 mg) in 245 adults with type 2 diabetes and overweight who were already taking metformin. The main goals were to see how well each dose lowered blood sugar and body weight over 40 weeks. Participants receiv…

This study followed 465 adults with type 2 diabetes in Spain who were already prescribed Rybelsus® (oral semaglutide) by their doctor. Researchers tracked changes in blood sugar levels, body weight, and how satisfied patients were with their treatment over 8-10 months. The goal w…

This study tested a year-long community program for 98 people with type 2 diabetes in Galveston. Participants received education, dietary advice, therapy, and help with social and financial needs. The goal was to see if this extra support could improve blood sugar levels, weight,…

This study tested a new insulin called icodec that is injected just once a week, compared to standard insulins taken every day. Over 1,000 adults with type 2 diabetes who had never used insulin before took part. The goal was to see if the weekly insulin controls blood sugar just …

This study tested whether adding oral diabetes drugs (metformin/pioglitazone or sitagliptin) to a short course of insulin can help newly diagnosed type 2 diabetes patients achieve long-term remission. 264 participants were followed for one year to see how many could stop medicati…

This study looked at how well the diabetes pill Rybelsus (oral semaglutide) controls blood sugar and weight in 650 Japanese adults with type 2 diabetes. Participants took the pill once daily as prescribed by their doctor and filled out a questionnaire during a regular visit. The …

This study tested whether adding semaglutide (a drug that helps lower blood sugar) to a new weekly insulin (insulin icodec) improves blood sugar control in people with type 2 diabetes. 148 adults with type 2 diabetes who were already on daily insulin took part. First, everyone re…

This study tested a program called My Diabetes Care (MDC) that helps people with type 2 diabetes manage their condition through a patient portal. About 458 adults took part, and researchers looked at changes in blood sugar levels, weight, and cholesterol. The goal was to see if u…

This study tested a new fast-acting insulin (NNC0471-0119) given through an insulin pump in 65 adults with type 2 diabetes. Researchers measured how quickly the insulin entered the bloodstream and how well it lowered blood sugar, comparing it to a standard insulin (insulin aspart…

This study tested an automated insulin delivery system (a smart pump) in 15 adults with type 1 or type 2 diabetes who also have advanced kidney disease or are on dialysis. Participants used the system for 8 weeks, then switched to their usual care for another 8 weeks. The goal wa…

This pilot study tested a mobile app and fitness trackers to give personalized diet and activity advice to 27 adults with type 2 diabetes or prediabetes. The goal was to improve blood sugar control and encourage healthier eating. The app used machine learning to tailor recommenda…

This study looked at how well oral semaglutide works for Thai adults with type 2 diabetes. Researchers reviewed medical records of 209 patients over 6 to 12 months to see changes in blood sugar (HbA1c) and body weight. The goal was to understand real-world effectiveness in a Thai…

This study tested whether a new way of making semaglutide works as well as the current version for controlling blood sugar in people with type 2 diabetes. 388 adults took a weekly injection of either the standard or the new semaglutide for about 8 months. The main goal was to see…

This small study tested a new artificial intelligence system that automatically controls blood sugar levels in people with type 2 diabetes. Three adults who use insulin at home had their glucose kept between 100-140 mg/dL for 24 hours while eating three standard meals. The goal w…

This study looked at how safe and tolerable a weekly shot of semaglutide (Ozempic) is for people with type 2 diabetes in Chile. 104 adults took part for about 24 weeks, getting a dose chosen by their doctor. Researchers tracked side effects and changes in blood sugar levels to co…

This study tested a new insulin, icodec, that is injected just once a week, against a standard daily insulin (glargine) in nearly 1,000 adults with type 2 diabetes who had never used insulin before. The goal was to see if the weekly insulin controls blood sugar as well as the dai…

This study tested whether adding pioglitazone or dapagliflozin to two common diabetes drugs (alogliptin and metformin) helps lower blood sugar more effectively. It involved 133 adults with type 2 diabetes whose blood sugar was not well controlled. The main goal was to see if one …

This study tested whether helping people with type 2 diabetes get their basic needs met—like food, housing, and safety—can improve their blood sugar control. About 473 adults on Medicaid took part. The goal was to see if a navigation program to address these needs could lower HbA…

This study looked at whether eating 3 low-calorie meals a day helps control blood sugar better than eating 5 small meals in people with type 2 diabetes who are overweight or obese. Fifty adults followed one of two diet plans for 11 weeks. Researchers measured blood sugar changes,…

This study looked at whether using a continuous glucose monitor along with help from a clinical pharmacist can improve blood sugar control in uninsured Black and Hispanic patients with type 2 diabetes. Twenty participants used the monitor and worked with the pharmacist to manage …

This study tested a medicine called tirzepatide in children and teenagers (ages 10 to 17) with type 2 diabetes that was not well controlled by their current treatments. The goal was to see if adding tirzepatide could safely lower blood sugar levels better than a placebo over abou…

This study tested whether using a continuous glucose monitor (CGM) in the hospital can help keep blood sugar levels in a safe range for people with type 1 or high-risk type 2 diabetes. 157 patients wore a wireless CGM that sent real-time glucose readings to a care team, who then …

This study looked at how high-intensity interval training (HIIT) affects blood sugar control in women with type 2 diabetes, comparing those before and after menopause. Sixty women aged 40-65 who were not regularly exercising took part in a supervised HIIT program. The goal was to…

This study tested a new medicine called AZD5004 in 406 adults with type 2 diabetes. The goal was to see if it lowers blood sugar better than a placebo or an existing drug. Participants had diabetes for at least 6 months and were on diet, exercise, or stable doses of metformin or …

This study tested whether taking colostrum (a supplement from cow's first milk) for 60 days could improve blood sugar, inflammation, and physical or mental performance in people with type 2 diabetes and healthy adults. About 80 participants were split into four groups: healthy or…

This study tested whether providing free, healthy meals and phone-based lifestyle coaching for 6 months can improve blood sugar levels and reduce food insecurity in adults with type 2 diabetes who have trouble affording food. 215 participants were randomly assigned to receive eit…

This study followed 187 adults with type 2 diabetes in Mexico who were already prescribed Rybelsus (oral semaglutide) by their doctors. The goal was to see how well the once-daily pill lowers blood sugar and affects body weight over 8-10 months. Participants completed questionnai…

This study looked at whether semaglutide, a type 2 diabetes medicine taken as a daily tablet, can lower the risk of serious heart problems like heart attack or stroke. Over 9,600 adults with type 2 diabetes and existing heart disease took either semaglutide or a placebo for up to…

This study followed 244 adults with type 2 diabetes in Japan who were prescribed Xultophy® by their doctors. Researchers tracked blood sugar levels and any low blood sugar episodes over 26 weeks. The goal was to see how well the drug works in everyday medical practice.

This study tested whether personalized, automatic coaching messages based on continuous glucose monitor readings and mood can help people with insulin-treated type 2 diabetes improve their blood sugar control. 46 adults completed the 12-week program. The goal was to see if this a…

This study tested whether delivering healthy food boxes along with simple educational materials could help people with type 2 diabetes who also struggle with food insecurity. About 100 adults with high blood sugar levels took part. The goal was to improve diet, increase physical …

This study looked at how well the diabetes pill Rybelsus (oral semaglutide) works in real-world settings for adults with type 2 diabetes. Researchers tracked changes in blood sugar levels and body weight over about 8-10 months. Participants took the medication as prescribed by th…

This study tested whether combining a home monitoring device with diabetes education and skills training helps African American adults with poorly controlled type 2 diabetes. About 200 participants used the FORA monitoring system for 12 months. The main goal was to see if their b…

This study tested a lifestyle program designed for rural families at high risk for heart disease and type 2 diabetes. Over 500 Hispanic and non-Hispanic adults participated, focusing on healthy eating, physical activity, and weight management. The goal was to see if a culturally …

This study tested a 6-month program that taught nutrition and exercise to 50 mothers and children in vulnerable communities in Mexico's Yaqui Valley. The goal was to improve lifestyle habits and reduce risks for heart disease and type 2 diabetes. Researchers measured weight, bloo…

This study tested a diabetes prevention program designed for college students facing challenges like food or financial insecurity. 80 UCLA undergraduates with prediabetes or high risk were split into two groups: one received a tailored 19-session program, the other got standard h…

This study tested whether mindfulness training helps people with type 2 diabetes better manage food cravings and stick to a low-carb diet. Sixty adults with type 2 diabetes who often ate in response to cravings participated. The goal was to see if mindfulness skills could reduce …

This study tested a treatment made from umbilical cord stem cells (called secretome) in 12 men with severe erectile dysfunction that did not improve with sildenafil (Viagra). All participants had type 2 diabetes. The goal was to see if the treatment was safe and could improve ere…

This study tested whether a 6-month online mindfulness program could help adults with uncontrolled type 1 or type 2 diabetes lower their blood sugar. Over 300 participants were randomly assigned to either mindfulness training or a stress management education class. The main goal …

This study looked at whether intermittent fasting (not eating for certain periods) can improve how well the pancreas makes insulin in people with early type 2 diabetes. 51 adults with diabetes and obesity took part. Researchers measured changes in beta-cell function and blood sug…

This study tested whether a special lighting setup could help people with mild Alzheimer's disease and type 2 diabetes sleep better and improve their blood sugar. 61 participants living in assisted living or nursing homes were exposed to either the special light or a regular ligh…

This study looked at whether a set of exercises called modified Otago exercises can help people with type 2 diabetes who have nerve damage in their feet. The exercises aim to improve balance, joint awareness, and overall physical fitness. 38 adults between 40 and 65 years old too…

This study tested whether eating house cricket powder before a meal could lower blood sugar spikes in people with type 2 diabetes. Twenty adults on metformin took cricket powder, whey protein, or a placebo mixed into soup, then had their blood sugar and insulin measured for two h…

This study looked at whether foot-ankle exercises or walking exercises can help people with type 2 diabetes who have nerve problems in their feet. 375 adults with diabetes were split into three groups: one did foot-ankle exercises, one did walking, and one received only standard …

This study looked at how easy and convenient the DuraTouch® device is for people with type 1 or type 2 diabetes. 128 participants used the device for about 12 weeks and rated their satisfaction. The goal was to see if the device makes diabetes management simpler and more convenie…

This study tested whether mindfulness training could reduce stress, anxiety, and depression in people with type 2 diabetes. 140 adults were randomly assigned to either a mindfulness program or standard care. Researchers measured changes using standard questionnaires. The goal was…

This study tested whether semaglutide, a diabetes medicine, improves walking ability in people with type 2 diabetes and peripheral artery disease (narrowed leg arteries). About 792 adults received weekly injections of semaglutide or a placebo for 59 weeks. The main goal was to me…

This early-stage study tested a new medicine called NNC0519-0130 in 20 Chinese men who were overweight or had obesity. The goal was to see how the drug moves through the body and if it is safe. Participants received either the drug or a placebo for about 28 weeks, with up to 7 di…

This study tested whether a smartphone app and a connected device help people with type 2 diabetes continue taking their Ozempic injections as prescribed. 304 participants who were already prescribed Ozempic used the app and attached a device to their injection pen. The study las…

This study aims to better understand and diagnose insulin allergy, a rare but serious condition in people with diabetes who need insulin to live. Researchers will test a step-by-step method to identify the exact cause of the allergy and study the immune system's role. The goal is…

This study looked at 67 adults with type 2 diabetes and fatty liver disease who were starting a type of diabetes medication called SGLT2 inhibitors. Researchers measured liver stiffness and fat using ultrasound and checked blood markers before and 6 months after starting the drug…

This study looked at 470 adults aged 18-75 with type 2 diabetes and metabolic syndrome to identify their Traditional Chinese Medicine (TCM) patterns. Researchers used a standard questionnaire and four TCM diagnostic methods to classify participants. The goal was to better underst…

This study looked at whether stopping certain diabetes medications (incretin-based therapies) before an upper endoscopy lowers the chance of having leftover food or liquid in the stomach that could interfere with the procedure or cause complications. 69 adults with type 2 diabete…

This study looked at whether two blood tests, eLIFT and FibroMeter, can accurately detect advanced liver fibrosis (scarring) in people with type 2 diabetes. The researchers compared these blood tests to a specialized ultrasound (FibroScan) and, in some cases, liver biopsy. The go…

This study tested a new long-acting insulin called insulin icodec in 18 children and adolescents aged 10 to 17 with type 2 diabetes. Participants received a single injection based on their body weight, and researchers measured how the drug moved through their bodies over about 8 …

This study looked at whether viruses in pregnant women with diabetes might increase the risk of congenital heart defects in their babies. Researchers analyzed blood and stool samples from 114 women to detect enteroviruses and other viruses. The goal was to gather knowledge for fu…

This study looked at whether a new diabetes medicine (NNC0519-0130) changes how the body processes a common birth control pill. It also checked if the drug affects how fast the stomach empties. The study involved 47 healthy women past menopause and lasted about 35 weeks. Results …

This study tested whether a pop-up alert in the electronic medical record could help doctors refer patients with fatty liver disease (NASH) to a liver specialist. Thirty doctors from internal medicine, family medicine, and endocrinology took part. The goal was to see if the alert…

This study looked at how the diabetes drug rongliflozin is processed in people with mild or moderate liver damage compared to healthy people. 32 adults took a single dose of the drug, and researchers measured drug levels in the blood and checked for side effects. The goal was to …

This study tested a program that helps low-income African Americans with diabetic kidney disease get their basic needs met, like food or housing. 50 people took part to see if the program was practical and could improve blood sugar, blood pressure, and quality of life. The goal w…

This study looked at how breathing and recovery after a short walk differ between people with type 2 diabetes who use insulin and those who don't. Researchers tested 70 adults with breathing tests and a 6-minute walk. The goal was to see if insulin use is linked to weaker breathi…

This study aimed to uncover the genetic and lifestyle factors that cause pre-diabetes to turn into type 2 diabetes. Over 1,700 healthy adults aged 18 to 55 underwent detailed tests of how their bodies handle sugar and store fat. Researchers hope these findings will lead to better…

This study looked at over 28,000 people with type 2 diabetes and a specific type of heart failure (HFpEF) to compare two drugs: tirzepatide and semaglutide. The goal was to see which one better prevents death or hospitalization due to heart failure. The research used existing med…

This study looked at how different levels of kidney function affect a new medicine called NNC0519-0130 for type 2 diabetes. Thirty-six adults with normal, mildly, moderately, or severely reduced kidney function received a single dose. Researchers measured the drug levels in their…

This study looked at why people of Black African and Caribbean descent have a higher risk of type 2 diabetes. Researchers compared how quickly the stomach empties a sugary drink in 30 white Europeans and 30 people of Black heritage. They also measured blood sugar and hunger-relat…

This study looked at how inherited genes influence the way people respond to two common diabetes medications, metformin and glipizide. Over 1,000 adults at risk for or with type 2 diabetes took part. Researchers measured blood sugar and insulin levels after taking the drugs to se…

This study looked at health records from over 58,000 people to see if using real-world data can produce the same results as a controlled clinical trial. The researchers focused on the drug semaglutide for patients with type 2 diabetes and a type of heart failure. The goal was to …

This study examined 240 Kazakh adults newly diagnosed with diabetes to understand how their bodies handle insulin and how their immune system reacts early on. Researchers measured blood sugar, insulin resistance, and inflammation markers to find differences between types of adult…

This study aimed to find the smallest amount of fatty acids that can temporarily cause mild insulin resistance in healthy volunteers. Nine participants received a fat infusion to see how it affects their body's ability to use insulin. The results will help design future studies o…

This study tested whether a family history app can help doctors collect and use information about your family's health to make better decisions. Over 600 adults aged 30-69 took part. The goal was to see if the app increases the number of patients with family history recorded in t…

This study tested a new decision-support tool called PREVENT to help nurses prioritize patients moving from hospital to homecare. Researchers looked at whether using the tool reduced the number of patients readmitted to the hospital within 60 days. About 1,900 adults with conditi…

This study tested a culturally adapted program called DM-BOOST para Latinx to help Spanish-speaking Latinx adults with type 2 diabetes better manage their condition. The program used behavioral economics and technology to encourage patients to attend diabetes education classes an…

This study looks at over 158,000 people with type 2 diabetes to see if injectable semaglutide reduces the risk of heart attacks, strokes, or death. Researchers are using existing medical records to mimic a previous clinical trial. The goal is to learn how well real-world data can…

This study looked at how type 2 diabetes works in children and young adults aged 12 to 25. Researchers gave some participants insulin shots to give their pancreas a rest and checked if that helped insulin production. They also compared diabetic and non-diabetic volunteers to lear…

This study looked at over 200,000 adults with obesity and type 2 diabetes to see if the type of diabetes medication they took before a cancer diagnosis affected their survival and health after cancer. Researchers compared GLP-1 receptor agonists (like Ozempic) with other diabetes…

This study looked at ways to help more people with type 2 diabetes attend diabetes self-management classes. Researchers tested different approaches, including using electronic health record prompts and peer support, to see what works best. The study involved 32 participants and a…

This study tested how well a new device called GLUCUBE measures blood sugar in 52 adults with type 2 diabetes. The goal was to see if the device becomes more accurate the more people use it. Results were compared to a standard blood sugar meter.

This study tested a program that used a Fitbit activity tracker and text messages to help Hispanic teenagers with obesity become more active and improve their sleep. The study included 43 teens aged 14-16 who owned a cellphone. The main goal was to see if the program was practica…

This study looked at 172 people with and without HIV to understand why those with HIV have a higher risk of diabetes. Researchers examined fat tissue and blood to see if immune cells in fat are linked to insulin resistance. The goal was to learn more about the connection, not to …

This study looked at how semaglutide, a diabetes medication, affects stem cells that help keep blood vessels healthy. Researchers measured changes in stem cell numbers and function in 10 adults with type 2 diabetes over 24 weeks. The goal was to understand the drug's effects on b…

This study looked at how semaglutide, a diabetes medicine, affects the kidneys in people with type 2 diabetes and chronic kidney disease. About 106 participants received either semaglutide or a placebo injection once a week for a year. Researchers used MRI scans, blood and urine …

This study looked at how attending different amounts of a diabetes education program affects self-care, emotional distress, and quality of life in people with type 2 diabetes. 120 participants were split into groups that completed 100%, 60%, or 10% of the program, or had delayed …

This study looked at 202 people with type 2 diabetes and early-stage diabetic eye disease (non-proliferative diabetic retinopathy). Researchers used painless, non-invasive eye scans to track changes over time. The goal was to find early warning signs that the disease is getting w…

This study looked at whether a health coaching program designed with input from immigrant communities can help people with type 2 diabetes better manage their condition. Researchers compared this culturally sensitive approach to standard care in 202 first-generation immigrants. T…

This study looked at how a drug called LCZ696 (used for heart failure) affects the kidneys and heart in 72 people with type 2 diabetes, some with early signs of heart stiffness and some without. Participants received a salt solution to test their body's response. The goal was to …

This study looked at whether large sets of health insurance claims can be used to get the same results as a traditional clinical trial for a heart failure drug. Researchers analyzed data from over 11,000 people with type 2 diabetes and a certain type of heart failure. The goal wa…

This is a long-term observational study that has been tracking the health of residents of the Gila River Indian Community since 1965. The purpose is to understand what causes Type 2 diabetes and its complications, like heart and eye problems. Eligible community members receive re…