Can a 20-Hour fast help your pancreas?

NCT ID NCT05717127

Completed Disease control Sponsor: Mount Sinai Hospital, Canada Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether intermittent fasting (eating only within a 4-hour window each day) can improve how well the pancreas makes insulin in people with early type 2 diabetes. 51 adults with type 2 diabetes and obesity took part. The goal was to see if this eating pattern could slow the decline in beta-cell function, which is a key cause of diabetes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: intermittent fasting (time-restricted feeding with 20 hours fasting and 4-hour eating window)
What this could lead to: If it works, this could point toward a simple lifestyle approach to help preserve insulin production in early type 2 diabetes.
What could go wrong: This is a small, completed study with only 51 participants. Results may not apply to everyone, and the fasting schedule may be hard to maintain long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETES MELLITUS, TYPE 2 OBESITY

Contacts and locations

Locations

Leadership Sinai Centre foe Diabetes - Mount Sinai Hospital

Toronto, Ontario, M5T 3L9, Canada

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