Mount Sinai Hospital, Canada

This study is testing whether active surveillance (watchful waiting) is as safe as surgery for people with low rectal cancer who have a complete response after chemoradiotherapy. About 90 participants will be monitored for 2 years to see how often the cancer returns and whether d…

This study tests whether a mobile app that sends daily health check-ins can reduce unplanned hospital visits after colorectal surgery. About 670 adults from three Canadian hospitals will either receive standard follow-up care or use the app for 30 days after discharge. The app as…

This pilot study looks at pregnant women with mechanical heart valves to see if using low molecular weight heparin (LMWH) plus low dose aspirin works as well as the standard blood thinner warfarin to prevent dangerous clots around the valve. The study will check if it is possible…

This study tests whether giving two medicines (acetaminophen and ibuprofen) together works better than ibuprofen alone to close a common heart blood vessel in extremely premature infants (born before 27 weeks). About 310 babies will take part. The goal is to see if the combo redu…

This study tests whether time-restricted eating—fasting for 18 hours and eating only during a 6-hour window each day—can help preserve the pancreas's ability to produce insulin and improve blood sugar control in people with type 2 diabetes. Over 52 weeks, 112 overweight adults wi…

This study looks at what happens when people stop taking the weight-loss drug semaglutide. Researchers want to see if slowly reducing the dose over 16 weeks helps maintain weight loss and heart health better than stopping all at once. The study involves 98 adults with obesity who…

This study tests whether a carefully designed diet can change the gut bacteria in people with active ulcerative colitis and reduce disease activity. Twenty adults with mild to moderate colitis will follow the diet and have their gut bacteria and inflammation levels measured. The …

This study tests whether injecting a numbing medicine (ropivacaine) near a nerve in the pelvis can reduce pain after a hysterectomy done through small incisions. Sixty women will be randomly assigned to get either the real injection or a sham (fake) injection. Their pain levels w…

This study looks at whether raising the head and torso 25 degrees helps people with severe obesity (BMI over 40) breathe better through a facemask while under general anesthesia. Fifty adults scheduled for elective surgery will be placed in both a flat and a head-elevated positio…

This study tests a digital tool called the Digital Bridge, which connects hospital and primary care communication systems to improve care transitions for older adults with multiple chronic conditions. Researchers will enroll 640 patients aged 60 and older from two hospital system…

This study looks at whether watching short educational videos before a first sarcoma clinic visit helps patients and their caregivers learn more about the disease and possible treatments. About 100 adults with advanced sarcoma (or their caregivers) who have not had prior treatmen…