Drug cocktail may save tiniest Babies' hearts and lungs
NCT ID NCT05340582
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving two medicines (acetaminophen and ibuprofen) together works better than ibuprofen alone to close a common heart blood vessel in extremely premature infants (born before 27 weeks). About 310 babies will take part. The goal is to see if the combo reduces death or severe lung disease, and improves development at 18-30 months.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Centre Hospitalier de l'Université Laval
NOT_YET_RECRUITINGQuébec, Quebec, G1V 4G2, Canada
Contact
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John Hunter Hospital
ACTIVE_NOT_RECRUITINGNewcastle, New South Wales, 2300, Australia
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McMaster Children's Hospital
RECRUITINGHamilton, Ontario, L8N 3Z5, Canada
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Mount Sinai Hospital
RECRUITINGToronto, Ontario, M5G 1X5, Canada
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Prince of Wales Hospital
NOT_YET_RECRUITINGShatin, NT, Hong Kong
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Royal Alexandra Hospital
RECRUITINGEdmonton, Ontario, T5H 3V9, Canada
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Royal North Shore Hospital
RECRUITINGSt Leonards, New South Wales, 2065, Australia
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Sunnybrook Health Sciences Centre
RECRUITINGToronto, Ontario, M4N 3M5, Canada
Contact
Contact
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The Rotunda Hospital
ACTIVE_NOT_RECRUITINGDublin, Ireland