New drug combo could save tiny hearts and lungs in preterm infants

NCT ID NCT05340582

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 23 times

Summary

This study tests whether giving two medicines together (acetaminophen and ibuprofen) works better than ibuprofen alone to close a common heart blood vessel in extremely premature babies. About 310 infants born before 27 weeks will take part. The goal is to reduce death and severe lung disease by treating the condition more effectively.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Hospitalier de l'Université Laval

    NOT_YET_RECRUITING

    Québec, Quebec, G1V 4G2, Canada

    Contact

  • John Hunter Hospital

    ACTIVE_NOT_RECRUITING

    Newcastle, New South Wales, 2300, Australia

  • McMaster Children's Hospital

    RECRUITING

    Hamilton, Ontario, L8N 3Z5, Canada

    Contact

  • Mount Sinai Hospital

    RECRUITING

    Toronto, Ontario, M5G 1X5, Canada

    Contact

  • Prince of Wales Hospital

    NOT_YET_RECRUITING

    Shatin, NT, Hong Kong

    Contact

  • Royal Alexandra Hospital

    RECRUITING

    Edmonton, Ontario, T5H 3V9, Canada

    Contact

  • Royal North Shore Hospital

    RECRUITING

    St Leonards, New South Wales, 2065, Australia

    Contact

  • Sunnybrook Health Sciences Centre

    RECRUITING

    Toronto, Ontario, M4N 3M5, Canada

    Contact

    Contact

  • The Rotunda Hospital

    ACTIVE_NOT_RECRUITING

    Dublin, Ireland

Conditions

Explore the condition pages connected to this study.