Can a common painkiller prevent a heart problem in preemies?

NCT ID NCT07067177

First seen Apr 26, 2026 · Last updated May 06, 2026 · Updated 2 times

Summary

This study tested whether giving paracetamol (a common painkiller) through an IV can prevent a heart opening called patent ductus arteriosus (PDA) in extremely premature infants. About 40 babies born before 30 weeks or weighing less than 1250 grams were randomly given either paracetamol or indomethacin (the standard drug). The goal was to see which drug works better at closing the opening, with follow-up including heart scans and blood tests.

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Contacts and locations

Locations

  • Al Ahli Hospital

    Hebron, Palestinian Territories

  • Makassed

    East Jerusalem, Palestinian Territories

  • Palestine Medical Complex

    Ramallah, Palestinian Territories

Conditions

Explore the condition pages connected to this study.