New study weighs risks of treating vs. watching heart defect in preemies
NCT ID NCT03456336
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether actively treating a heart condition called patent ductus arteriosus (PDA) in premature babies is better than simply monitoring it. About 482 infants born between 22 and 28 weeks of pregnancy will be followed to see which approach reduces the risk of death or long-term lung problems. The goal is to help doctors make safer decisions for these fragile newborns.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Brown University - Women and Infants Hospital of Rhode Island
Providence, Rhode Island, 02905, United States
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Case Western Reserve University, Rainbow Babies and Children's Hospital
Cleveland, Ohio, 44106, United States
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Cincinnati Children's Medical Center
Cincinnati, Ohio, 45267, United States
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Duke University
Durham, North Carolina, 27710, United States
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Emory University
Atlanta, Georgia, 30303, United States
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Northwestern Lurie Children's Hospital of Chicago
Chicago, Illinois, 60611, United States
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RTI International
Durham, North Carolina, 27705, United States
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Research Institute at Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
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Sharp Mary Birch Hospital for Women & Newborns
San Diego, California, 92123, United States
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Stanford University
Palo Alto, California, 94304, United States
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University of Alabama at Birmingham
Birmingham, Alabama, 35233, United States
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University of Iowa
Iowa City, Iowa, 52242, United States
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University of Mississippi Medical Center - Children's of Mississippi
Jackson, Mississippi, 39216, United States
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University of New Mexico
Albuquerque, New Mexico, 87131, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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University of Rochester
Rochester, New York, 14642, United States
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University of Texas Health Science Center at Houston
Houston, Texas, 77030, United States
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University of Texas Southwestern Medical Center at Dallas
Dallas, Texas, 75235, United States
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University of Utah
Salt Lake City, Utah, 84108, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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