Could a common painkiller be safer for Preemies' hearts?

NCT ID NCT04037514

First seen Jan 09, 2026 · Last updated May 12, 2026 · Updated 23 times

Summary

This study tested if paracetamol works as well as ibuprofen to close a common heart blood vessel (PDA) in 133 premature babies. Both drugs aim to close the vessel without surgery. The goal is to find which treatment is safer and more effective for these fragile infants.

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Contacts and locations

Locations

  • Hospital Materno-Infantil (Hospital Regional Carlos Haya) Málaga:

    Málaga, Málaga, Spain

  • Hospital Reina Sofía

    Córdoba, Cordoba, Spain

  • Hospital Universitari i Politècnic La Fe

    Valencia, Valencia, 46026, Spain

  • Hospital Universitario de Cabueñes

    Gijón, Gijón, Spain

Conditions

Explore the condition pages connected to this study.