Simple blood test may spot heart risk in preemies
NCT ID NCT07338370
First seen Jan 17, 2026 · Last updated Jun 23, 2026 · Updated 27 times
Summary
This study looks at whether levels of a substance called PGE2 in the blood can predict which premature babies (born at 32 weeks or earlier) will develop a serious heart condition called patent ductus arteriosus (PDA). Researchers will measure PGE2 levels and use heart ultrasounds in 34 infants. Some babies will receive ibuprofen to close the duct, while others are observed. The goal is to find a way to identify high-risk infants early.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Faculty of Medicine, Ain Shams, University
RECRUITINGCairo, Abbasia, 11517, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ibuprofen
What this could lead to
If successful, this could help doctors identify which preterm infants are at risk for a serious heart condition, allowing earlier treatment.
What could go wrong
This is a small, early observational study. Results may not apply to all preterm infants, and the link between PGE2 levels and PDA may not be strong enough to guide treatment.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.