16-Hour daily fast tested as diabetes therapy

NCT ID NCT07272460

Recruiting now Disease control Sponsor: Mount Sinai Hospital, Canada Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether time-restricted eating—fasting for 18 hours and eating only during a 6-hour window each day—can help preserve the pancreas's ability to produce insulin and improve blood sugar control in people with type 2 diabetes. Over 52 weeks, 112 overweight adults will either follow this eating schedule or standard lifestyle advice. The goal is to see if this simple dietary change can slow diabetes progression.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: time-restricted eating (behavioral intervention)
What this could lead to: If it works, this could point toward a simple, drug-free way to help preserve insulin production and improve blood sugar control in early type 2 diabetes.
What could go wrong: This is a mid-sized trial (112 people) testing a behavioral change, which can be hard to stick with long-term. Results may not apply to everyone, and the benefit might be modest.

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Conditions

The condition(s) this trial relates to.

Intermittent Fasting Overweight type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OVERWEIGHT (BMI > 25) TYPE 2 DIABETES

Contacts and locations

Locations

Leadership Sinai Centre for Diabetes
RECRUITING

Toronto, Ontario, M5T3L9, Canada

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