Massive Pre-Diabetes study seeks clues to stop type 2 diabetes

NCT ID NCT00340132

First seen Jun 26, 2026 · Last updated Jul 17, 2026 · Updated 4 times

Summary

This completed study looked at 1759 adults aged 18-55 to uncover why some people develop type 2 diabetes. Researchers measured how the body handles sugar, uses energy, and stores fat, and also collected genetic samples. The goal was to find genetic and lifestyle factors that lead to insulin resistance and diabetes, which could help predict and prevent the disease in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could identify genetic markers and environmental factors that predict type 2 diabetes, potentially guiding future prevention strategies.
What could go wrong
This is an observational study, not a treatment trial, so it will not directly benefit participants. Findings may not lead to immediate clinical applications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Insulin Resistance Obesity obesity disorder Overweight type 2 diabetes mellitus Weight Gain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • NIDDK, Phoenix

    Phoenix, Arizona, 85004, United States

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