Sugar substitutes may trigger blood clotting, study warns

NCT ID NCT04731363

First seen Jun 27, 2026 · Last updated Jul 14, 2026 · Updated 2 times

Summary

This study looks at whether drinking a beverage with artificial sweeteners (erythritol or xylitol) changes how blood platelets clump together, which could affect heart attack or stroke risk. Researchers will measure platelet activity and blood levels of these sweeteners in 50 healthy adults before and after consumption. The goal is to understand if these common sugar substitutes might increase cardiovascular risk.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

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Other studies related to the condition(s) this trial covers.