DIABETES MELLITUS TYPE 2

This early-stage study tests a new experimental medicine (NNC1679-0001) for type 2 diabetes. Researchers want to see if it is safe and how the body handles it. About 80 healthy adults and people with type 2 diabetes will receive a single injection of either the study drug or a pl…

This study tests whether a smartphone app that shows real-time blood sugar and activity data can help 100 teens and young adults with type 2 diabetes improve their glucose control. Participants use a continuous glucose monitor, Fitbit, and the Healthmine app for 90 days, then are…

This study looks at how well the drug tirzepatide works for weight loss and blood sugar control in everyday medical practice in Paraguay. It will include 160 adults: 80 with obesity but no diabetes, and 80 with type 2 diabetes (with or without obesity). All participants will take…

This study looks at whether a common diabetes medication (GLP-1 RA) can help older women over 65 with type 2 diabetes maintain muscle strength and bone health. Twenty participants will take the drug as part of their regular care and undergo tests like grip strength and bone densi…

This study tests a once-weekly injection called CagriSema (cagrilintide plus semaglutide) in 80 children and teens with type 2 diabetes. The goal is to see if it lowers blood sugar and body weight better than a placebo. The study lasts about 1 year and 3 months, with all particip…

This study will monitor about 600 adults with type 2 diabetes who are starting Rybelsus as part of their normal care. The goal is to track any side effects and how well the medicine controls blood sugar over 26 weeks. Participants take the pill as prescribed by their doctor, with…

This study tests a new weekly injection, NNC0487-0111, against the approved drug semaglutide in 1000 adults with overweight or obesity and type 2 diabetes. Participants will receive two weekly shots (one active, one placebo) for about a year. The main goal is to see how much weig…

This study looks at how safe and effective the Endogenex System is for people with type 2 diabetes. It includes 50 adults who previously received a sham (fake) treatment in an earlier study. The main goal is to track any serious side effects related to the device or procedure.

This study tests an experimental medicine, CagriSema, to see how well it lowers blood sugar in people with type 2 diabetes. About 400 adults aged 18-64 with stable diabetes will receive one of two versions of the drug, given by different injection devices. The study lasts about 3…

This study tests a new program for adults with type 2 diabetes who are leaving the hospital. The program screens for unmet social needs (like food or housing) and provides a navigator to help address them. About 412 participants will be compared to usual care to see if the progra…

This study tests a virtual program called STRIDE for adults aged 21-44 who were recently diagnosed with type 2 diabetes and are raising a child aged 2-14. The program teaches practical skills like prioritizing self-care, healthy eating, and family physical activity. Researchers w…

This study will test a special education program designed to boost confidence in managing type 2 diabetes. 400 adults will either take the program or get standard care. The goal is to see if the program helps with blood sugar monitoring, diabetes knowledge, and quality of life.

This study tests an experimental injection called IN-B00009 in adults with type 2 diabetes whose blood sugar is not well controlled by diet and exercise alone. About 110 participants will receive either the drug or a placebo for 24 weeks. The main goal is to see if the drug lower…

This early-stage study tests a new single pill (UI087) against taking three separate diabetes drugs together in healthy adults. The goal is to see if the combination pill is safe and how the body absorbs it. 44 participants will receive both treatments at different times to compa…

This study tests a new medicine called SHR-3167 in adults with type 2 diabetes whose blood sugar is not well managed by current pills. About 90 people will receive different doses to see how safe it is and how well it controls blood sugar. The main goal is to check for low blood …

This study tests a new medicine called NNC0662-0419 for people with type 2 diabetes. About 270 adults will receive either the new drug, an approved drug (semaglutide), or a placebo as a weekly injection. The goal is to see if the new drug safely lowers blood sugar and helps with …

This study is testing whether a 12-week education program delivered through WhatsApp, which involves a family member, can help people with type 2 diabetes better manage their condition. The program sends educational materials and quizzes to both the person with diabetes and their…

This study tests an 8-week program that sends encouraging messages to help adults with type 2 diabetes become more active and feel better. About 20 participants will use their smartphones to receive these messages. The goal is to see if the program is easy to use and helpful.

This study tests whether a wearable device that vibrates the calf can help improve blood sugar control in adults with type-2 diabetes. About 305 participants in Saudi Arabia will use the device at home for 12 weeks while seated. The goal is to see if this simple, low-effort activ…

This study will test two different exercise programs—Modified Otago Exercises and Dynamic Neuromuscular Stabilization Exercises—in 36 older adults with type 2 diabetes and nerve damage in their feet. The goal is to see which program better improves balance and the ability to perf…

This study is testing a new, noninvasive device called the Argus CGM that uses light and AI to estimate blood sugar levels without needles. Up to 100 adults with type 1 diabetes, type 2 diabetes, or prediabetes will wear the device for 15 days while researchers collect data to im…

This study looks at how older adults (55+) with type 2 diabetes use continuous glucose monitors and activity trackers to manage their health. Researchers want to see if these devices help people sit less and improve blood sugar control. Sixty participants will wear the devices an…

This study will test a new screening program to find 50-year-olds in Italy who are at risk for type 2 diabetes and heart disease but haven't been diagnosed yet. About 3,000 people will be invited for a check-up using simple questionnaires. Based on their risk scores, they'll get …

This study will follow 2800 Chinese adults aged 18-60 who are overweight or obese for five years. Researchers want to see how their health changes over time, especially whether they develop type 2 diabetes or related complications. Participants will use a smartphone app to track …

This study looks at whether a mobile app called Fabla-diabetesMM, which lets people record audio diaries, is easy and helpful for older adults with type 1 or 2 diabetes who also have other health conditions. Thirty participants will use the app and answer questions about their ex…

This study looks at the gut bacteria of 270 adults in New Caledonia to understand how they relate to obesity and type 2 diabetes. Researchers will analyze stool samples to find connections between microbes, diet, and health. The goal is to gather knowledge, not to test a treatmen…

This study will use a safe, painless neck ultrasound to look for early signs of artery hardening in 96 adults who have both type 2 diabetes and moderate chronic kidney disease. The goal is to find out how common hidden artery disease is in this high-risk group and how it relates …

This registry will follow 500 people with type 2 diabetes who have already been treated with the Endogenex System. The goal is to collect long-term safety data by tracking any device- or procedure-related side effects. Participants must agree to share their medical records and at…