DIABETES MELLITUS TYPE 2

This study is testing whether adding a procedure that cuts specific stomach nerves (truncal vagotomy) to a standard weight-loss surgery (Roux-en-Y gastric bypass) leads to better remission of type 2 diabetes. Researchers will compare the two surgical approaches in 40 adults with …

This study is testing whether a simple, home-based vibration device worn on the calf can help people with type-2 diabetes better control their blood sugar. Researchers in Saudi Arabia will enroll 305 previously inactive adults to use either a real vibration device, a fake (sham) …

This study is testing whether a smartphone app that shows real-time blood sugar and activity data can help adolescents and young adults with type 2 diabetes better control their condition. For 90 days, participants will use the app along with a continuous glucose monitor and a Fi…

This study will monitor the safety and effectiveness of Rybelsus (oral semaglutide) in 600 Korean adults with type 2 diabetes during routine medical care. Participants will take Rybelsus as prescribed by their doctor and be followed for about 26 weeks. The research aims to collec…

This study is testing whether a 12-week education program delivered through WhatsApp can help people with type 2 diabetes better manage their condition. The program involves both the person with diabetes and a supportive family member, who will receive educational materials and q…

This study is testing a new support program for adults with type 2 diabetes who are leaving the hospital. The program uses a computer survey to identify social challenges like housing or food insecurity and then pairs patients with a helper for 90 days. Researchers want to see if…

This study is testing a weekly injection called CagriSema to see if it helps children and teenagers with type 2 diabetes better control their blood sugar and reduce their body weight. About 80 participants, aged 10 to 18, will be randomly assigned to receive either the real medic…

This study is testing a new weekly injection called IN-B00009 for adults with type 2 diabetes whose blood sugar is not well managed by diet and exercise alone. About 110 participants will receive either the real injection or a placebo (dummy shot) for 24 weeks to see if it safely…

This study offers a medical device treatment to people with type 2 diabetes who were in the placebo group of a previous trial. It aims to collect real-world safety and performance data on the Endogenex System, which is designed to help control blood sugar. The study will enroll a…

This study aims to see if a new weekly injection called NNC0487-0111 is safe and works better than the approved drug semaglutide for people with both excess weight and type 2 diabetes. About 1,000 adults will be randomly assigned to receive either the new drug or semaglutide, bot…

This study is testing a new weekly injection called NNC0662-0419 to see if it can help control blood sugar and body weight in people with type 2 diabetes. It will compare the new drug to a placebo (a dummy shot) and to an already approved diabetes medication, semaglutide. The goa…

This study aims to check how safe and effective the medication tirzepatide is for adults in India who have type 2 diabetes or who are overweight/obese. About 344 participants will receive the medication for 46 weeks. Researchers will monitor side effects, weight changes, and bloo…

This study is testing a new drug called SHR-3167 for adults whose type 2 diabetes isn't well-managed with current pills. It will compare two methods for adjusting the drug dose: a standard fixed plan and a plan tailored to each person. The main goal is to see which method is safe…

This study aims to see how well an experimental medicine called CagriSema helps lower blood sugar in people with type 2 diabetes. Researchers will compare two different injection devices to deliver the same medicine. About 400 adults will participate for approximately 38 weeks to…

This study aims to see if a common type 2 diabetes medication (GLP-1 RAs like semaglutide) affects muscle strength and bone health in older women. It will observe 20 women over age 65 for 6 months while they take the medication as part of their normal care. Researchers will measu…

This study will monitor the safety and effectiveness of Ozempic (semaglutide) in 600 Korean adults with type 2 diabetes during their regular medical care. Participants will receive Ozempic as prescribed by their doctor, and researchers will track their health outcomes for about 6…

This study is testing if drinking regular milk can help prevent type 2 diabetes in adults who are lactose intolerant and have pre-diabetes. Researchers will enroll 40 participants to drink either lactose-containing or lactose-free milk for 12 weeks. The goal is to see if the milk…

This small pilot study is testing whether an 8-week program of text messages from an AI can help adults with type 2 diabetes become more physically active and feel better. The program involves setting weekly activity goals and doing well-being exercises. Researchers will check if…

This study aims to see which of two different exercise programs works better to improve balance and the ability to perform daily tasks for older adults with diabetic nerve pain. Researchers will compare a modified Otago exercise program with a neuromuscular stabilization program.…

This study is testing whether an audio diary mobile app is easy and helpful for older adults who have diabetes along with other chronic health conditions. Researchers want to see if using the app to record daily experiences affects how people manage their health. The main goal is…

This study is testing a new health screening program to find people at risk for type 2 diabetes and heart disease before they develop symptoms. It will invite 3,000 healthy 50-year-olds in an Italian province to answer health questions and get simple tests. The goal is to see if …

This research study aims to understand how gut bacteria differ between healthy people and those with obesity and type 2 diabetes in New Caledonia. Researchers will collect stool, blood, and urine samples from 270 adults across three groups: obese with diabetes, obese without diab…

This study is testing how easy it is to use a new wrist-worn device called the Argus CGM. The device uses light sensors and artificial intelligence to estimate blood sugar levels without needing to prick the skin. About 100 adults with type 1 diabetes, type 2 diabetes, or prediab…

This registry aims to collect long-term safety and health outcome information from people with type 2 diabetes who have already been treated with the Endogenex System. It will follow up to 500 participants for five years to monitor their health after the procedure. The goal is to…

This study aims to find out how common early artery disease is in people who have both type 2 diabetes and chronic kidney disease. Researchers will use a simple, safe neck ultrasound to check for early signs of artery hardening in 96 participants. The goal is to gather informatio…