Lotus seed supplement shows promise for diabetic nerve pain

NCT ID NCT06778018

Completed Disease control Sponsor: Riphah International University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This completed study tested whether lotus seed capsules could improve nerve health, blood sugar, and immune function in 60 people with type 2 diabetes and nerve damage. Participants took either lotus seed or placebo capsules for 9 months alongside their regular diabetes treatment. Researchers measured changes in body mass index, blood sugar, cholesterol, liver and kidney function, nerve damage scores, and immune markers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Lotus seed (Nelumbo nucifera) capsules
What this could lead to: If it works, this could point toward a natural supplement to help manage diabetic nerve damage and improve blood sugar control.
What could go wrong: This is a small, completed trial with only 60 participants, so results may not apply to everyone. Dietary supplements can have variable effects and are not a substitute for standard diabetes care.

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Conditions

The condition(s) this trial relates to.

diabetic kidney disease diabetic polyneuropathy type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETES MELLITUS, TYPE 2 DIABETIC NEPHROPATHIES

Contacts and locations

Locations

Riphah international university

Lahore, Punjab Province, 54000, Pakistan

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