New fast-acting insulin tested against standard in diabetes trial

NCT ID NCT04588259

Completed Disease control Sponsor: Novo Nordisk A/S Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new fast-acting insulin (faster aspart) against a standard insulin (NovoRapid) in 331 adults with type 1 or type 2 diabetes. Both were taken with a long-acting insulin (insulin degludec) for 16 weeks. The goal was to see if the new insulin works better at controlling blood sugar, especially after meals.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: fast-acting insulin aspart
What this could lead to: If it works, this could offer a faster-acting insulin option for better blood sugar control after meals.
What could go wrong: This is a completed Phase 3 trial, but results may not show meaningful improvement over existing insulins. Risks include low blood sugar and injection site reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

type 1 diabetes mellitus type 1 diabetes mellitus 1 type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETES MELLITUS, TYPE 1 DIABETES MELLITUS, TYPE 2

Contacts and locations

Locations

Anhui Provincial Hospital-Endocrinology

Hefei, Anhui, 230001, China
Beijing Chao-Yang Hospital, Capital Medical University-Endocrinology

Beijing, Beijing Municipality, 100020, China
Beijing Pinggu Hospital-Endocrinology

Beijing, Beijing Municipality, 101200, China
Cangzhou People's Hospital-Endocrinology

Cangzhou, Hebei, 061000, China
Central Hospital of Minhang District, Shanghai-Endocrinology

Shanghai, Shanghai Municipality, 201199, China
Changzhou No.2 People's Hospital, Yanghu Branch

Changzhou, Jiangsu, 213003, China
China-Japan Union Hospital of Jilin University-Endocrinology

Changchun, Jilin, 130033, China
Chinese People's Liberation Army General Hospital-Endocrinology

Beijing, Beijing Municipality, 100853, China
Chongqing University Three Gorges Hospital

Chongqing, Chongqing Municipality, 404000, China
First Affiliated Hospital of Kunming Medical University-Endocrinology

Kunming, Yunnan, 650032, China
General Hospital of Tianjin Medical University-Endocrinology

Tianjin, Tianjin Municipality, 300052, China
Hengshui People's Hospital (Harrison International Peace Hospital)-Endocrinology

Hengshui, Hebei, 053000, China
Inner Mongolia People's Hospital-Endocrinology

Hohhot, Inner Mongolia, 010020, China
Jiangsu Province Hospital-Endocrinology

Nanjing, Jiangsu, 210029, China
Jiangxi Provincial People's Hospital-Endocrinology

Nanchang, Jiangxi, 330006, China
Jinan Central Hospital Affiliated to Shandong University

Jinan, Shandong, 250013, China
Master Centre for Hong Kong

Kowloon, Hong Kong
Nanjing Jiangning Hospital-Endocrinology

Nanjing, Jiangsu, 211199, China
Prince of Wales Hospital

Shatin, New Territories, Hong Kong
Qinghai Provincial People's Hospital

Xining, Qinghai, 810007, China
Shanghai Fifth People's Hospital-Endocrinology

Shanghai, Shanghai Municipality, 200240, China
Shanghai Tenth People's Hospital (Tenth People's of Tongji University)-Endocrinology

Shanghai, Shanghai Municipality, 200072, China
Sun Yat-sen Memorial Hospital, Sun Yat-sen University

Guangzhou, Guangdong, 510120, China
Suzhou Municipal Hospital-Endocrinology

Suzhou, Jiangsu, 215002, China
Tangshan Gongren Hospital-Endocrinology

Tangshan, Hebei, 063000, China
The Affiliated Hospital of Jiangsu University-Endocrinology

Zhenjiang, Jiangsu, 212001, China
The Fifth Medical Center of PLA General Hospital-Endocrinology

Beijing, Beijing Municipality, 100071, China
The First Affiliated Hospital of Anhui Medical University-Endocrinology

Hefei, Anhui, 230061, China
The First Affiliated Hospital of Soochow University

Suzhou, Jiangsu, 215006, China
The First Bethune hospital of Jilin University-Endocrinology

Changchun, Jilin, 130061, China
The First People's Hospital of Yunnan Province-Endocrinology

Kunming, Yunnan, 650032, China
The General Hospital of the PLA Rocket Force-Endocrinology

Beijing, Beijing Municipality, 100088, China
The Second Affiliated Hospital of Guangxi Medical University-Endocrinology

Nanning, Guangxi, 530006, China
The Second Affiliated Hospital of Kunming Medical University

Kunming, Yunnan, 650101, China
The Second Affiliated Hospital of Nanjing Medical University-Endocrinology

Nanjing, Jiangsu, 210011, China
The Second Affiliated Hospital of Shantou University Medical College-Endocrinology

Shantou, Guangdong, 515065, China
The Second Hospital of Hebei Medical University-Endocrinology

Shijiazhuang, Hebei, 050000, China
The Second Hospital of Jilin University

Changchun, Jilin, 130041, China
The affiliated Hospital of Inner Mongolia Medical University-Endocrinology

Hohhot, Inner Mongolia, 010050, China
Yueyang Central Hospital-Endocrinology

Yueyang, Hunan, 414000, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.