Diabetes drug showdown: which Add-On works best?

NCT ID NCT03499704

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether adding pioglitazone or dapagliflozin to standard diabetes pills (alogliptin and metformin) helps control blood sugar better in adults with type 2 diabetes. A total of 133 participants took one of the two extra drugs for 26 weeks. The main goal was to see which combination lowered HbA1c (a measure of blood sugar control) more effectively.

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ajou University Hospital

    Suwon, Gyeonggi-do, 16499, South Korea

  • Chosun University Hospital

    Gwangju, 61453, South Korea

  • Daejeon Eulji Medical Center, Eulji University

    Daejeon, 35233, South Korea

  • Inje University Haeundae Paik Hospital

    Busan, 48108, South Korea

  • Kangbuk Samsung Hospital

    Seoul, 03181, South Korea

  • Korea University Anam Hospital

    Seoul, 02841, South Korea

  • Kyung Hee University Hospital at Gangdong

    Seoul, 05278, South Korea

  • Pusan National University Hospital

    Busan, 49241, South Korea

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Seoul National University Bundang Hospital

    Seongnam-si, Gyeonggi-do, 13620, South Korea

  • The Catholic University of Korea, Bucheon, St. Marys Hospital

    Bucheon-si, Gyeonggi-do, 14647, South Korea

  • The Catholic University of Korea, ST. Vincents Hospital

    Suwon, Gyeonggi-do, 16247, South Korea

  • Ulsan University Hospital

    Ulsan, 44033, South Korea

  • YeungNam University Hospital

    Daegu, 42415, South Korea

  • Yonsei University Health System Severance Hospital

    Seoul, 03722, South Korea