New diabetes pill shows promise in early safety trial

NCT ID NCT04426474

First seen May 27, 2026 · Last updated Jun 23, 2026 · Updated 4 times

Summary

This early-stage study tested an oral drug called LY3502970 in 68 adults with type 2 diabetes. The main goal was to check safety and side effects, while also measuring how the drug moves through the body and affects blood sugar. Participants took the drug or a placebo for up to 18 weeks, with frequent visits and blood tests.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Clinical Pharmacology of Miami

    Hialeah, Florida, 33014, United States

  • Endeavor Clinical Trials

    San Antonio, Texas, 78229, United States

  • Hassman Research Institute

    Marlton, New Jersey, 08053, United States

  • Midwest Clinical Research Unit

    Dayton, Ohio, 45417, United States

  • Profil Institut für Stoffwechselforschung

    Neuss, North Rhine-Westphalia, 41460, Germany

  • Profil Mainz

    Mainz, 55116, Germany

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

LY3502970 (oral drug)

What this could lead to

If successful, this could lead to a new oral medication to help control blood sugar in people with type 2 diabetes.

What could go wrong

This is an early Phase 1 trial focused on safety, not effectiveness. The drug may cause side effects or fail to improve blood sugar in larger studies.

Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.