Drug combo shows promise for weight loss in severe obesity
NCT ID NCT03968224
First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 39 times
Summary
This study looked at whether adding dapagliflozin to metformin helps people with prediabetes or type 2 diabetes and severe obesity lose more weight than metformin alone. About 160 participants took either both drugs or just metformin for up to 12 months. The main goal was to see if the combination leads to at least 10% more weight loss. The study also checked changes in blood pressure and waist size.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Hospital de Especialidades Centro Médico Nacional Siglo XXI
Mexico City, 06720, Mexico
Conditions
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