Drug combo shows promise for weight loss in severe obesity

NCT ID NCT03968224

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether adding dapagliflozin to metformin helps people with prediabetes or type 2 diabetes and severe obesity lose more weight than metformin alone. About 160 participants took either both drugs or just metformin for up to 12 months. The main goal was to see if the combination leads to at least 10% more weight loss. The study also checked changes in blood pressure and waist size.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital de Especialidades Centro Médico Nacional Siglo XXI

    Mexico City, 06720, Mexico

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