Can Weight-Loss surgery change how blood pressure drugs work?

NCT ID NCT03535376

Recruiting now Knowledge-focused Sponsor: Norwegian University of Science and Technology Source: ClinicalTrials.gov ↗

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This study looks at how bariatric surgery, such as gastric bypass or sleeve gastrectomy, affects the way the body absorbs the blood pressure medication valsartan. Researchers will measure drug levels in the blood of 12 patients before and after surgery to see if the operation changes how much of the drug reaches the bloodstream. The goal is to understand whether medication doses need to be adjusted after these procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: valsartan
What this could lead to: If successful, this could help doctors adjust blood pressure medication doses for patients after bariatric surgery, ensuring the drugs work effectively.
What could go wrong: This is a small, early study with only 12 participants, so results may not apply to everyone. The findings will describe how the body processes the drug, not whether the surgery is safe or effective.

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Conditions

The condition(s) this trial relates to.

morbid obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY, MORBID

Contacts and locations

Locations

St. Olavs University Hospital
RECRUITING

Trondheim, Norway

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