Massive diabetes study tracks thousands over decades to uncover disease secrets

NCT ID NCT00339482

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This long-running study follows over 12,000 people from the Gila River Indian Community in Arizona to understand why type 2 diabetes develops and how it leads to complications. Participants receive regular check-ups every two years, including blood tests and physical exams. The goal is to learn about the causes and natural history of diabetes, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could reveal key factors that cause or worsen type 2 diabetes, helping to develop better prevention and treatment strategies.

What could go wrong

This is an observational study, not a treatment trial, so it won't directly provide a cure or new therapy. Results may not apply to other populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder diabetes mellitus kidney disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • NIDDK, Phoenix

    Phoenix, Arizona, 85014, United States