Fat infusion study aims to unlock diabetes clues
NCT ID NCT03479671
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed early-phase study tested different doses of fatty acids (Intralipid) in 9 healthy volunteers to find the dose that causes mild insulin resistance. The goal was to create a reliable model for future diabetes research. Participants received low or medium doses of fat infusion, and their insulin sensitivity was measured.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Intralipid (fatty acid infusion)
- What this could lead to
- If successful, this could help researchers design better studies on how fat affects insulin resistance, potentially leading to new diabetes treatments.
- What could go wrong
- This is a very small, early-phase study with only 9 healthy volunteers, so results may not apply to people with diabetes or other conditions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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