INSULIN SENSITIVITY

This study is testing if a simple change to meal timing can help night shift workers. Researchers want to see if restricting eating to a specific daily window (time-restricted eating) can improve blood pressure and how the body processes sugar. They are recruiting 50 long-term ni…

This study aims to see if replacing sugary drinks with stevia-sweetened beverages helps children aged 8-12 control their weight and improve metabolic health. About 150 children will be randomly assigned to drink either a sugary beverage, a stevia beverage, or flavored water for 8…

This study is testing whether a minimally invasive endoscopic procedure to reduce stomach size, combined with lifestyle changes, is better than lifestyle changes alone for treating a serious fatty liver disease called MASH in people with obesity. Researchers will compare the two …

This study is testing whether colchicine, an anti-inflammatory medication, can help people with type 1 diabetes use insulin more effectively. Researchers are enrolling 26 adults who have type 1 diabetes with signs of ongoing inflammation and reduced insulin sensitivity. Participa…

This study is testing whether giving insulin in short weekly sessions can improve how the body uses sugar and help with thinking and memory problems in people with Alzheimer's disease. Eight adults with Alzheimer's will receive the insulin treatment once a week for six months whi…

This early-stage study is testing a new drug called retatrutide to see how it affects the body's ability to produce and respond to insulin in people with type 2 diabetes. It will involve about 95 adults and compare the new drug against a placebo and another existing diabetes medi…

This study aims to find out if consuming the artificial sweeteners sucralose or aspartame affects blood sugar control in older adults who have prediabetes. Researchers will provide all meals for 8 weeks to 30 participants and closely monitor their blood sugar levels and inflammat…

This study aims to find out if consuming two common artificial sweeteners, saccharin and acesulfame potassium, affects blood sugar control in older adults who have prediabetes. Researchers will feed 30 participants carefully controlled diets for 8 weeks, with some receiving the s…

This study aims to understand how a single session of leg exercise improves how muscles respond to insulin, which helps control blood sugar. Researchers will study 8 healthy young men by having them do one-legged exercise, then measuring blood and muscle samples over several hour…