Artificial sweeteners under scrutiny: could they worsen prediabetes?

NCT ID NCT05337098

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether the artificial sweeteners aspartame and sucralose affect blood sugar control in adults aged 40 and older with prediabetes. Participants will receive either one of the sweeteners or a placebo as part of their diet for 8 weeks. Researchers will monitor blood sugar levels continuously and through glucose tolerance tests to see if these sweeteners impair glucose regulation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

aspartame and sucralose (artificial sweeteners)

What this could lead to

If it works, this could show that certain artificial sweeteners harm blood sugar control in older adults with prediabetes, guiding safer dietary choices.

What could go wrong

This is a small, early-stage study with only 30 participants. Results may not apply to everyone, and the sweeteners may have no effect.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PREDIABETES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Insulin Resistance prediabetes syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Virginia Tech

    RECRUITING

    Blacksburg, Virginia, 24061, United States

    Contact