Can insulin eye drops quench dry eyes?

NCT ID NCT06939959

Completed Disease control Sponsor: Khyber Teaching Hospital Source: ClinicalTrials.gov ↗

First seen Aug 14, 2026 · Last updated Aug 14, 2026

Summary

This trial tests whether insulin eye drops can improve the ocular surface in people with moderate-to-severe dry eye disease. Participants will receive either insulin eye drops or artificial tears for up to a year. The study measures changes in dry eye symptoms and tear production over 12 weeks. The goal is to see if insulin, a hormone known for blood sugar control, can also help restore the eye's surface.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: insulin eye drops
What this could lead to: If effective, insulin eye drops could offer a new treatment option for people with moderate-to-severe dry eye disease, potentially improving symptoms and tear production.
What could go wrong: This is a single-center trial with 128 participants, and results may not apply to everyone. Insulin eye drops may cause irritation or other side effects, and the benefit over artificial tears is not yet proven.

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Conditions

The condition(s) this trial relates to.

dry eye syndrome Insulin Resistance

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DRY EYE INSULIN SENSITIVITY

Contacts and locations

Locations

Khyber Teaching Hospital

Peshawar, Khyber Pukhtunkhwa, 25000, Pakistan

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