COLORECTAL CANCER

This study tested a new two-drug combination (MK-4280A) in 441 people with advanced colorectal cancer that had spread and no longer responded to standard treatments. The goal was to see if the new treatment helps people live longer compared to usual care. The approach uses immuno…

This study tested a cancer vaccine called ETBX-011 in 43 people with advanced cancers (colorectal, lung, breast, or prostate) that make a protein called CEA. The vaccine uses a modified virus to teach the immune system to attack cancer cells. The main goals were to check safety a…

This early-stage study tested a new drug called GDC-1971 combined with standard treatments for advanced lung or colorectal cancer. The main goal was to check safety and find the right dose in 10 patients. It is a first step to see if this combination might help control these canc…

This study tested a combination of three drugs (nivolumab, trametinib, and ipilimumab) in 325 people with advanced colorectal cancer that had spread and was previously treated. The goal was to see if the combination could shrink tumors or slow the disease. This is not a cure, but…

This study tested a new drug called CBX-12 in 69 adults with advanced solid tumors (like ovarian, lung, or breast cancer) that had stopped responding to standard treatments. The goal was to find a safe dose and see if the drug could shrink tumors. The study was completed, but res…

This study tested a combination of three drugs (encorafenib, binimetinib, and cetuximab) given before surgery to people with a specific type of colorectal cancer that has a BRAF V600E mutation. Only 2 participants were enrolled. The goal was to see how well the drugs shrink the t…

This early-stage study tested a new treatment called VE800 combined with the immunotherapy drug nivolumab in 56 people with advanced or metastatic cancers like melanoma, stomach, and colorectal cancer. The main goal was to see if the combination is safe and whether it can shrink …

This study tested a new computer-based tool that helps doctors adjust chemotherapy doses for people with cancers of the digestive system (like colorectal or stomach cancer). The goal was to reduce unplanned treatment delays caused by low blood cell counts. 52 adults receiving FOL…

This study tested a treatment for people with colorectal cancer that spread to the liver. A small pump placed under the skin delivers chemotherapy directly to the liver through an artery. The goal was to see if this approach could shrink liver tumors and help patients live longer…

This early-phase study tested the safety and best dose of combining two drugs, regorafenib and nivolumab, in 52 people with advanced colorectal cancer that had stopped responding to standard treatments. The goal was to see if this combination could help control the disease. Parti…

This study tested an immunotherapy drug called prolgolimab in 30 people with stage II-III colorectal cancer that has a specific genetic feature (MSI/dMMR). Participants received the drug for 6 months before surgery. The main goal was to see if the cancer completely disappeared by…

This early-phase study tested an experimental drug called SHR-A1811 in 101 people with advanced stomach or colorectal cancers that have a specific marker (HER2). The goal was to find a safe dose and see if the drug can shrink tumors. Participants had cancers that stopped respondi…

This early-stage study tested a new drug called CUE-102 in 42 adults with certain advanced cancers (colorectal, stomach, pancreatic, or ovarian) that had returned or spread and were no longer responding to standard treatments. The goal was to find a safe dose and see if the drug …

This study compared three ways to find precancerous polyps during colonoscopy: using an AI system alone, a special cap alone, or both together. About 481 adults undergoing screening took part. The goal was to see if the combination finds more polyps than either method by itself, …

This study tested the drug tislelizumab given before surgery in 33 people with early-stage (stage II-III) colorectal cancer that has specific genetic changes (MSI-H or dMMR). The goal was to see if the drug could shrink or eliminate the tumor before surgical removal. The main mea…

This early-phase study tested a custom-made yeast vaccine designed to teach the immune system to recognize and attack leftover cancer cells. Five adults with different solid tumors (like colorectal, breast, or lung cancer) who had already completed curative treatment received the…

This study tested whether a Medtronic pump and Codman catheter could safely deliver chemotherapy directly to the liver in 35 people with colorectal cancer or bile duct cancer that spread to the liver. The goal was to see if this device combination is a safe alternative to an olde…

This early-phase study tested an experimental oral drug called JAB-3312 in 40 adults with advanced solid tumors (such as lung, colon, or breast cancer) that had stopped responding to standard treatments. The main goal was to find a safe dose and understand side effects. Participa…

This study tested a new drug called SAR444245 (THOR-707) combined with other cancer treatments in 138 adults with advanced or metastatic gastrointestinal cancers, including esophageal, stomach, liver, and colorectal cancers. The goal was to see if the combination could shrink tum…

This study tested a drug called axitinib against a placebo in 52 people with advanced colorectal cancer that had spread to the liver and stopped responding to at least two chemotherapy treatments. The goal was to see if axitinib could help control the cancer and to test a new ult…

This early-phase study tested whether adding two drugs (romidepsin and 5-azacitidine) to an immunotherapy (MK-3475) could help people with a specific type of advanced colorectal cancer called microsatellite stable (MSS). The study included 27 adults whose cancer had already sprea…

This early-phase study tested a combination of two drugs, cabozantinib and TAS-102, in 15 people with metastatic colorectal cancer that had stopped responding to standard treatments. The main goal was to find the safest dose and check for side effects. The study is complete and h…

This early-stage study tested a new drug (BI 765049) alone or with another drug (ezabenlimab) in 21 Asian adults with advanced solid tumors like lung, stomach, or liver cancer. The goal was to find a safe dose and see if the drugs could shrink tumors. Participants received infusi…

This early-phase study tested a new drug called TPST-1495, alone or with pembrolizumab, in 89 people with advanced solid tumors (like colorectal, lung, or head and neck cancer) that had stopped responding to standard treatments. The main goal was to find the safest dose and check…

This study tested an experimental drug called BMS-813160, given alone or with chemotherapy and/or the immunotherapy nivolumab, in 332 people with advanced colorectal or pancreatic cancer. The main goals were to check safety and side effects, and to see if the drug combination cou…

This study tested a combination of two drugs, lenvatinib and pembrolizumab, in 611 people with advanced cancers that had stopped responding to standard treatments. The cancers included triple-negative breast, ovarian, gastric, colorectal, glioblastoma, biliary tract, and pancreat…

This early-phase trial tested how well people with colorectal cancer tolerate a heated chemotherapy drug called raltitrexed, given directly into the abdomen during surgery. The goal was to find a safe dose and check for side effects. 30 patients took part, and the study is now co…

This study tested a combination of the targeted drug cetuximab with a strong chemotherapy mix (FOLFIRINOX) as a first treatment for people whose colorectal cancer had spread and could not be removed by surgery. The goal was to see how many patients had their tumors shrink or disa…

This study tested whether a high-protein drink with added arginine could reduce complications after colorectal surgery in 44 malnourished adults. Participants received either the arginine-enriched drink or a standard high-protein drink before and after surgery. Researchers tracke…

This early-phase study tested a drug called revumenib in 42 adults with colorectal cancer or other solid tumors that had worsened after at least one prior treatment. The main goals were to check safety, find the right dose, and see if the drug could shrink tumors or slow cancer g…

This study tested a device called Colovac+ in 27 adults with colorectal cancer who had surgery to remove part of their colon. The device is placed inside the body to protect the new surgical connection and keep it clean while it heals. The goal was to see if it could reduce compl…

This early-phase study tested the safety of combining the immunotherapy drug pembrolizumab with targeted radiation (SBRT) in 15 adults with colorectal cancer that had spread only to the liver. After surgery to remove all visible tumors, participants received the combination to se…

This early-phase study tested a drug called gevokizumab alongside standard cancer treatments in 167 adults with advanced colorectal, stomach, or kidney cancer. The goal was to find a safe dose and see if the combination helps control tumor growth. While not a cure, it aims to imp…

This study looked at whether a structured physical activity program, along with health education materials, could help prevent colon cancer from returning in people who had surgery and chemotherapy for high-risk stage II or stage III colon cancer. A total of 889 participants were…

This study looked at whether taking vitamin D and aspirin daily, along with exercise and a low-fat diet, could help prevent colorectal cancer from returning in 16 patients who had no visible tumors but still had cancer DNA in their blood. The goal was to see if these lifestyle ch…

This early-phase study tested a new drug called SNB-101 in 21 people with advanced solid tumors (like colorectal, breast, or lung cancer) that had stopped responding to standard treatments. The drug is a nanoparticle version of SN-38, a chemotherapy agent, given by IV on days 1 a…

This study tested whether more intense chemotherapy could help people with colorectal cancer that has spread to the liver and cannot be fully removed by surgery. 124 adults received either standard treatment or one of three stronger chemotherapy combinations. The goal was to see …

This study tested a new drug combination (MK-4280A) in Chinese adults with advanced colorectal cancer that had spread and was no longer responding to standard treatments. The goal was to see if the new combo helps people live longer compared to usual care. About 94 participants t…

This study tested a chemotherapy pill (TAS-102) combined with targeted radiation for people with colorectal cancer that has spread to the liver. The goal was to find the safest dose and see how well the combination controls tumor growth. About 52 adults with 1 to 4 liver tumors t…

This early-phase trial tested an experimental immunotherapy called ELI-002 in 25 people with KRAS-mutated pancreatic, colorectal, lung, ovarian, or bile duct cancers who had minimal residual disease (small amounts of cancer left after standard treatment). The goal was to see if t…

This study looked at whether giving nutrition through a small vein in the arm (peripheral parenteral nutrition) helps patients recover better after colorectal surgery. The trial included 200 adults who had surgery for conditions like colorectal cancer or inflammatory bowel diseas…

This study looked at whether a care plan led by a geriatrician and a nurse could help older adults (70+) with cancer live longer and feel better. It included 792 people with different cancers like breast, lung, or prostate. The approach was compared to usual cancer care to see if…

This study tested the drug nivolumab in 35 people with a certain type of advanced colorectal cancer that had not responded to standard treatments. The goal was to see if the drug could stop the cancer from growing for at least 27 weeks. The trial focused on patients whose cancer …

This study tested a new blood test designed to find colorectal cancer early in people at average risk. Nearly 49,000 adults aged 45 to 85 gave a blood sample before their routine colonoscopy. The goal was to see how well the blood test could detect cancer and advanced growths com…

This study tested whether a camera capsule (pill) could be used as a first step in bowel cancer screening to decide who needs a colonoscopy. Over 2,000 people from the Danish screening program took part. The goal was to see if this approach increases screening participation, find…

This study tested a new imaging agent called [18F]FAPI-74 in 109 people with gastrointestinal cancers, including liver, bile duct, stomach, pancreas, and colorectal cancers. The goal was to see if this PET scan could better detect cancer cells compared to standard methods. Resear…

This study tested whether ultrasound can detect nerve damage caused by the chemotherapy drug oxaliplatin in people with gastrointestinal cancer. Twenty participants who had or were receiving oxaliplatin and had nerve symptoms were scanned. The goal was to see if ultrasound could …

This study tested whether a new at-home stool DNA test (Cologuard) could help more Alaska Native people get screened for colorectal cancer, which is very common in this group. Over 2,000 adults who were due for screening were randomly assigned to receive the test with extra suppo…

This study tested a community-based program to increase colorectal cancer screening in rural China. Over 20,000 adults aged 45-70 took part. The program used questionnaires and fecal tests to identify high-risk individuals and encouraged them to get a colonoscopy. The goal was to…

This study tested a program to increase colorectal cancer screening in 12 Appalachian counties. Over 5,400 adults aged 50-74 took part. Clinics and communities worked together to encourage screening, with the goal of catching cancer early and saving lives.

This study looked at 60 spouses of people who had colorectal cancer. The goal was to see if giving them extra education and support would make them more likely to complete a simple at-home screening test (FIT kit) for colorectal cancer. The researchers compared two groups to find…

This study looked at the best ways to encourage childhood cancer survivors who are at high risk for colorectal cancer to get screened. About 300 survivors who had radiation to their belly or spine and had not been screened recently took part. Researchers compared different method…

This study tested whether sending reminders (outreach) and offering screening during clinic visits (inreach) could increase colorectal cancer screening rates. Over 600 adults aged 50 to 75 who were not up-to-date with screening took part. The goal was to see if these strategies w…

This study looked at two ways to screen for colorectal cancer in healthy people aged 50 to 69: a one-time colonoscopy versus yearly stool tests. The goal was to see which method finds more early signs of cancer and how they compare in terms of benefits, risks, and use of medical …

This study looked at whether taking magnesium supplements could reduce the risk of colorectal cancer in people with a specific genetic makeup. Researchers gave 250 participants either magnesium or a placebo for 12 weeks and measured changes in colon tissue markers linked to cance…

This study tested whether a personalized nursing approach—including tailored counseling before surgery, careful body temperature and positioning during surgery, and targeted recovery guidance after—could improve outcomes for 90 patients having laparoscopic colorectal cancer surge…

This pilot study tested whether offering free legal services early to people with advanced colorectal cancer could reduce stress and financial worries. Twenty participants received personalized legal help from a nonprofit for six months. The study measured changes in stress, copi…

This study looked at whether doing special exercises before colorectal cancer surgery helps people recover better afterward. 761 adults scheduled for surgery were split into two groups: one received prehabilitation training instructions, and the other got standard care. The main …

This small pilot study tested a new mind-body program designed to help female survivors of colorectal and anal cancer improve their sexual well-being. Six participants joined group sessions to learn coping skills and address body image changes. The goal was to see if the program …

This study tested a specially designed corset to help people with colorectal cancer feel more comfortable during continuous 5-FU chemotherapy infusion. Forty patients were split into two groups: one used the corset, the other received standard care. The goal was to see if the cor…

This study looked at whether Reiki, a gentle touch therapy, can help people who had surgery for colorectal cancer feel less pain and anxiety and recover faster. 64 patients took part, and researchers measured their pain, anxiety, and vital signs before and after Reiki sessions. T…

This study tested a mobile app called PainPac designed to help people with colorectal cancer manage pain. Researchers wanted to see if the app was easy to use and acceptable to patients. The app uses real-time assessments and can connect with electronic medical records to improve…

This study tested a web-based support program for people with colorectal cancer. 24 patients were split into two groups: one got the online program plus usual care, the other got usual care alone. The goal was to see if the program helped reduce symptoms and improve quality of li…

This study looked at two oral chemotherapy drugs, Xeloda and UFT with folinic acid, for people with advanced or metastatic colorectal cancer. The main goal was to find out which treatment patients preferred after trying both. The study also checked how safe each drug was. 89 adul…

This study looked at whether applying diclofenac gel to the hands and feet can prevent or delay hand-foot syndrome, a common and painful side effect of the chemotherapy drug capecitabine. About 150 people with colorectal or stomach cancer were observed. The goal was to see if the…

This study tested whether neurotropin can prevent or reduce nerve damage caused by the chemotherapy drug oxaliplatin in people with stage II or III colorectal cancer. 333 participants received either neurotropin or a placebo during their treatment. The goal was to see if neurotro…

This study tested whether N-Acetylcysteine, a common supplement, could protect colorectal cancer patients from nerve damage caused by the chemotherapy drug oxaliplatin. 46 adults with stage II or III colorectal cancer took part. Researchers measured neuropathy symptoms and inflam…

This study looked at 304 adults who had colorectal cancer surgery to see if using skin glue (tissue adhesive) or skin staples leads to fewer wound infections and lower costs. The goal was to find out which method is better for healing and affordability. Results will help doctors …

This study tested a digital tool (a chatbot) to help cancer survivors learn about genetic testing for hereditary cancer risk. 50 adults who had certain cancers (like breast, ovarian, or prostate) took part. The goal was to see if the chatbot was easy to use and if it helped more …

This study compared two at-home colorectal cancer screening tests (FIT and Cologuard) in over 5,000 patients from community health centers who were overdue for screening. The goal was to see which test more people completed and which was more practical in that setting. Participan…

This study tested a program that uses computer algorithms and patient navigators to help people in low-income areas complete their colorectal cancer screening. 385 adults from specific Philadelphia zip codes who had not finished a colonoscopy or stool test were included. The goal…

This study looked at whether a special website or coaching phone calls could help more people with a personal or family history of certain cancers get genetic testing. Over 800 participants were randomly assigned to use a mobile website, receive two motivational coaching calls, o…

This study looked at whether offering a blood-based screening test could encourage people who had previously avoided colonoscopy or stool tests to get screened for colorectal cancer. Researchers enrolled 297 adults aged 45-75 who had not completed a recommended screening. The goa…

This study looked at 598 people who had surgery to remove colorectal cancer. Researchers wanted to learn how often the cancer comes back after five years. By understanding this, doctors hope to create better follow-up plans and improve survival.

This study tested a multi-level program to increase colorectal cancer screening and follow-up in federally qualified health centers serving disadvantaged populations. The program included provider education, reminders, and patient navigation. The goal was to see if these combined…

This study looked at whether a simple frailty test (Edmonton Frailty Index) can predict complications after colorectal cancer surgery in people aged 65 and older. Researchers followed 200 patients for 30 days after surgery to track problems like infections, heart issues, and leng…

This study looked at whether sending text message reminders could boost the number of people who complete colorectal and breast cancer screening. Over 44,000 eligible adults participated. The goal was to see if simple SMS reminders are more effective than standard letters alone, …

This study looked at whether different social media messages can motivate people to follow colorectal cancer screening guidelines. Over 2,000 white or Black adults completed a survey after seeing one of five message types. Researchers measured how likely participants were to get …

This study looked at the gut bacteria of nearly 1,800 people who had colon polyps or colorectal cancer. The goal was to find bacterial patterns that could predict who is at high risk for cancer returning. Researchers hope this will lead to a simple stool test to catch colorectal …

This study examined how the COVID-19 pandemic affected colorectal cancer diagnosis and treatment in 198 patients in Hungary. Researchers compared cancer stages and diagnostic delays across different pandemic waves. The goal was to understand the impact of healthcare disruptions o…

This study looked at how well the drug T-DXd works compared to usual treatments for people with several types of advanced cancers that have high levels of a protein called HER2. Researchers used existing data from earlier trials and real-world medical records to compare outcomes.…

This study looked at 143 people in China who had repeat surgery after their first colorectal cancer operation failed or the cancer came back. The goal was to find out what factors help the surgery succeed and whether patients can eventually go to the bathroom normally again. Rese…

This study looked at the bacteria in the mouth and gut of 126 people to see if those with serrated polyposis syndrome have different bacteria than people without the condition. Researchers collected saliva and stool samples to compare bacterial types. The goal was to learn more a…

This study compared nurse practitioner monitoring to standard doctor monitoring for 207 people with colorectal cancer receiving intravenous chemotherapy. The goal was to see if nurses could provide equally safe and high-quality follow-up care. Results help determine if advanced p…

This study looked at whether a patient-centered approach called Value-Based Health Care can improve care for people with colorectal cancer. Researchers tracked medical results and patient feedback from 133 participants to see what works best. The goal was to help doctors and pati…

This study explored whether intestinal polyps release tumor cells or other substances into the blood that could signal early cancer spread. Researchers compared blood samples from 120 people with and without polyps. The goal was to find new biomarkers to improve monitoring and gu…

This study looked at how different diets affect gut bacteria and markers of colon cancer risk in 15 African American adults at higher risk for the disease. Participants ate both an animal-based diet high in fat and a plant-based diet low in fat to see changes in bacteria and bile…

This study gave 33 people with colorectal cancer the immune drug pembrolizumab before their surgery. Researchers wanted to see how the drug changed immune activity inside the tumor. The goal was to learn more about how the immune system responds, not to cure the disease.

This study tested a smartphone-based program to help African American men who were not up-to-date on colorectal cancer screening. 128 men received either the program (texts with videos) or standard educational texts. After 6 months, researchers checked medical records to see who …

This study tested a program called KanSurvive-ECHO to help rural primary care clinics provide better follow-up care for cancer survivors. Researchers worked with 15 clinics to improve tasks like scheduling cancer screenings, checking for distress, and tracking weight and tobacco …

This study gave educational materials about colorectal cancer and screening to 188 adults aged 45-75 in the Tampa Bay area. Researchers used surveys to measure changes in knowledge and intentions to get screened. The goal was to see if providing information can encourage more peo…

This study looked at 698 people with advanced colorectal cancer to see if inflammation in the body changes how well a targeted therapy (bevacizumab) combined with chemotherapy works. Researchers measured inflammation markers in the blood and tracked survival and tumor response. T…

This study looked back at the medical records of 500 people with colorectal cancer in two areas of China (Xinjiang and Shandong). The goal was to find out how long patients typically live after diagnosis and what factors affect their survival. Researchers collected information on…

This study looked at whether certain genetic changes in colon cancer tumors can help predict if the cancer will return after surgery. Researchers tested tumor tissue from 401 people with stage II or III colon cancer using a special method called QMPSF. The goal was to see if thes…

This study looked at 236 adults with breast, pancreatic, or colorectal cancer who came to the University of Colorado for a second opinion. Researchers wanted to understand what factors, like patient background or disease type, influence whether someone decides to stay at the new …

This study tested a program for older adults (ages 65-90) who had breast, colorectal, or prostate cancer. A community health worker assessed their health and provided coaching to address issues often missed after cancer treatment. The goal was to see if this approach is feasible …

This study involved 132 adults with colorectal cancer who had surgery to remove part of the colon and a temporary stoma. The goal was to better understand and define major complications from this standard treatment. Researchers hope this will help compare the safety of different …

This study tested a community-based program to help African Americans aged 45-75 get screened for colorectal cancer. The program provided education, risk assessment, and help with barriers like finding a doctor, transportation, and appointment scheduling. Researchers measured whe…

This study tested whether an educational program could help people in rural areas learn more about colorectal cancer screening. Researchers enrolled 205 adults aged 45-74 from specific counties in New Hampshire and Vermont. Participants completed surveys before and after the prog…

This study looked at whether teaching patients about Enhanced Recovery After Surgery (ERAS) before their operation helps them recover better. 88 adults with colorectal cancer were split into two groups: one got a special education session with a booklet, and the other got the usu…

This study looked at how a digital tool (eHNA) can help personalize care for people with colorectal cancer. Researchers interviewed 76 patients and clinicians to understand what works and what doesn't. The goal was to find ways to improve care planning and support for patients af…

This study measured how common colorectal cancer and pre-cancerous polyps are in endurance athletes aged 35 to 50. Researchers looked at 94 men and women who run long distances, like marathons or 50-mile races. The goal was to see if these athletes have different cancer rates com…

This study tested a training program for family doctors in Switzerland to see if it helps more patients get screened for colorectal cancer. Doctors in small groups learned how to discuss screening options like colonoscopy and stool tests with their patients. The study involved 44…

This study looked at whether two easy-to-use frailty questionnaires (G8 and VES-13) can predict serious side effects from chemotherapy in people 65 and older with gastrointestinal cancers. Researchers followed 72 patients before, during, and after treatment to see if frailty scor…

This study looked at whether a protein called tissue factor (TF) in the blood can help predict how serious colorectal cancer is and if it might come back. Researchers measured TF levels in 26 adults before and after surgery to remove their tumors. The goal was to see if higher TF…

This study looked at whether proteins in the blood can help screen for colorectal cancer. Researchers tested blood samples from 350 people aged 50 and older who were already scheduled for a colonoscopy. The goal was to see if certain protein markers could reliably detect advanced…

This study tested a decision aid for 60 adults aged 76-85 with low health literacy to help them decide about colorectal cancer screening. The goal was to see if the tool helped people make screening choices that matched their health and risk. The study measured changes in screeni…

This study looked at how drugs that interact with the body's endocannabinoid system (similar to cannabis) affect the movement of the colon. Researchers took healthy colon tissue from 36 colorectal cancer patients during surgery and tested these drugs in the lab. The goal was to u…

This study looked at whether eating walnuts can change the bacteria in your gut and reduce signs of colon cancer risk. About 140 adults at higher risk for colorectal cancer added walnuts to their diet for a month. Researchers measured changes in gut bacteria, inflammation, and su…

This study looked at whether using a balloon-assisted endoscope (G-Eye) together with artificial intelligence (CAD-Eye) finds more polyps than a standard colonoscopy with AI alone. About 341 people aged 50-74 who had a positive stool test took part. The goal was to see if the com…

This study tested a web-based app called STOMA Care to see if it is acceptable and helpful for bladder or colorectal cancer patients who need ostomy surgery and their caregivers. The app provides information and tools to improve stoma care knowledge, skills, and emotional well-be…

This study tested whether using an artificial intelligence system (ENDOAID) together with a small attachment called Endocuff helps doctors find more abnormal growths (polyps) in the colon during a colonoscopy. Over 1,700 adults aged 45-85 who needed a colonoscopy for screening or…

This study tested a 12-week web-based diet program with text messaging for 50 colorectal cancer survivors. The goal was to see if the program was easy to use and could help people eat more vegetables, whole grains, and fish while cutting back on red meat and sweets. Participants …

This study looked at people with advanced solid tumors (like lung, bladder, or skin cancer) who had been on immunotherapy (PD-1/PD-L1 inhibitors) for one year and whose disease was stable. It randomly assigned them to either stop treatment or continue until their cancer got worse…

This study looked at 56 people who had surgery for colon cancer that had not spread. Researchers wanted to see if the number and type of immune cells inside the tumor could help predict which patients might have a recurrence. They analyzed blood samples and tumor tissue to unders…

This study looked at how much say people felt they had in their care after a positive stool test for colorectal cancer. About 846 participants completed surveys about their experience and satisfaction with the screening and any follow-up procedures. The goal was to understand if …

This study looked at how colorectal and prostate cancer affect the energy centers (mitochondria) in muscle cells, and whether a 4-week home exercise program could improve them. Fifteen men awaiting surgery for these cancers did either resistance training or high-intensity interva…

This study looked at why some people develop colorectal polyps, which can lead to cancer. Researchers collected blood, urine, tissue samples, and lifestyle information from over 8,000 adults having a colonoscopy. The goal was to find biological, genetic, and lifestyle factors tha…

This study analyzed tumor and blood samples from 160 people with esophageal or rectal cancer to find genetic markers that might predict how well they respond to chemoradiotherapy before surgery. The goal was to better understand which patients benefit most from this treatment app…

This study enrolled 60 Spanish-speaking Latino adults from a church in Chapel Hill to see if an educational session could improve their knowledge of colorectal cancer and willingness to join cancer clinical trials. Participants watched videos in Spanish and completed questionnair…

This study tested whether wearable wristbands that track heart rate, sleep, and steps can help patients recover faster after colorectal cancer surgery. 192 patients wore the device for about a week after surgery and filled out daily forms. The goal was to see if early walking red…