Simple frailty quiz may help predict chemo risks for seniors with stomach or bowel cancer

NCT ID NCT07184047

Completed Knowledge-focused Sponsor: Ankara Etlik City Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether two simple frailty questionnaires (G8 and VES-13) can predict serious side effects from chemotherapy in people 65 and older with gastrointestinal cancers. Researchers followed 72 patients receiving standard chemotherapy and checked their frailty, nutrition, and muscle health over time. The goal is to help doctors tailor treatment to reduce harm in older, more vulnerable patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors identify which older patients are more likely to have severe side effects from chemotherapy, allowing for more personalized treatment plans.
What could go wrong: This is a small, single-center observational study, not a treatment trial. The results may not apply to all patients or settings, and the frailty scales may not be accurate enough to change practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

biliary tract cancer Biliary Tract Neoplasms chemotherapy-induced toxicity colorectal cancer colorectal neoplasm digestive system cancer digestive system neoplasm esophageal cancer Esophageal Neoplasms Frailty gastric cancer gastric neoplasm malignant pancreatic neoplasm Malnutrition nutritional deficiency disease sarcoglycanopathy Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BILIARY TRACT CANCER COLORECTAL CANCER ESOPHAGEAL CANCER (ESC) FRAILTY GASTRIC CANCER (GC) GASTROINTESTINAL CANCERS MALNUTRITION ELDERLY OLDER ADULTS (65 YEARS AND OLDER) PANCREATIC CANCER RESECTABLE SARCOPENIA IN ELDERLY TOXICITY DUE TO CHEMOTHERAPY

Contacts and locations

Locations

Etlik City Hospital, Medical Oncology Department

Ankara, Yenimahalle, 06210, Turkey (Türkiye)

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